Frailty in aging marks a state of decreased reserves resulting in increased vulnerability to
adverse outcomes when exposed to stressors. This Perspective synthesizes the evidence …

For several decades, understanding ageing and the processes that limit lifespan have
challenged biologists. Thirty years ago, the biology of ageing gained unprecedented …

Importance Research supports use of prehabilitation to optimize physical status before and
after colorectal cancer resection, but its effect on postoperative complications remains …

Summary The American Society of Anesthesiologists (ASA) physical status is a tool
commonly used to classify a patient's physical fitness before surgery. Since its introduction in …

The purpose of this guideline is to present evidence-based and consensus-based
recommendations for the prevention and treatment of postoperative delirium. The …

Answer questions and earn CME/CNE The concept of frailty has become increasingly
recognized as one of the most important issues in health care and health outcomes and is of …

Over the past 100 years, advances in medicine and public health have led to a nearly 2-fold
increase in average lifespan. 1 Approximately 8.5% of the global population is 65 years or …

Objectives The purpose of this systematic review and meta-analysis was to summarize the
prevalence of, and association between, physical frailty or sarcopenia and malnutrition in …

This narrative review presents a biological rationale and evidence to describe how the
preoperative condition of the patient contributes to postoperative morbidity. Any preoperative …

Cirrhosis is characterized by muscle wasting, malnutrition, and functional decline that confer
excess mortality not well quantified by the Model for End‐Stage Liver Disease (MELD) …