Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

An increasing number of therapies for spinal cord injury (SCI) are emerging from the
laboratory and seeking translation into human clinical trials. Many of these are administered …

Acute spinal cord injury (SCI) is one of the serious central nervous system injuries, which
can lead to significant neurological impairments and a reduction in quality of life with loss in …

The GTP-binding protein RhoA regulates microfilament dynamics in many cell types and
mediates the inhibition of axonal regeneration by myelin and chondroitin sulfate …

Desorption electrospray ionization (DESI) mass spectrometry (MS) is used in an imaging
mode to interrogate the lipid profiles of 15 μm thin tissue cross sections of injured rat spinal …

Limited axonal plasticity within the central nervous system (CNS) is a major restriction for
functional recovery after CNS injury. The small GTPase RhoA is a key molecule of the …

Arachidonic acid (ARA) and docosahexaenoic acid (DHA), which are the dominant
polyunsaturated fatty acids in the brain, have crucial roles in brain development and …

Study Design: Systematic review. Objective: Spinal cord injuries (SCIs) resulting in motor
deficits can be devastating injuries resulting in millions of health care dollars spent per …

In recent years, an increasing number of studies have been published, focusing on the
potential therapeutic use of small catalytic agents with strong biological properties. So far …

Introduction The approved analgesic and anti-inflammatory drugs ibuprofen and
indometacin block the small GTPase RhoA, a key enzyme that impedes axonal sprouting …