Macrophage scavenger receptors: Tumor support and tumor inhibition

E Kazakova, P Iamshchikov, I Larionova… - Frontiers in …, 2023 - frontiersin.org
Tumor-associated macrophages (TAMs) are a heterogeneous population of myeloid cells
that constitute up to 50% of the cell mass of human tumors. TAMs interact with the …

Immunopathogenesis of Nipah virus infection and associated immune responses

B Brown, T Gravier, I Fricke, SA Al-Sheboul, TN Carp… - Immuno, 2023 - mdpi.com
Pandemics in the last two centuries have been initiated by causal pathogens that include
Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (eg, the H1N1 pandemic of 2009) …

Antibiotics treatment promotes vasculogenesis in the brain of glioma-bearing mice

M Rosito, J Maqbool, A Reccagni, O Giampaoli… - Cell Death & …, 2024 - nature.com
In recent years, several studies described the close relationship between the composition of
gut microbiota and brain functions, highlighting the importance of gut-derived metabolites in …

Genome-wide landscape of runs of homozygosity and differentiation across Egyptian goat breeds

AM Sallam, H Reyer, K Wimmers, F Bertolini… - BMC genomics, 2023 - Springer
Understanding the genomic features of livestock is essential for successful breeding
programs and conservation. This information is scarce for local goat breeds in Egypt. In the …

[HTML][HTML] MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcoma

BK Nirala, TD Patel, L Kurenbekova, R Shuck… - JCI insight, 2023 - ncbi.nlm.nih.gov
Osteosarcoma (OS) is the most common primary bone tumor of childhood. Approximately
20%–30% of OSs carry amplification of chromosome 8q24, which harbors the oncogene c …

Construction and validation of a novel prognostic model of neutrophil‑related genes signature of lung adenocarcinoma

Q Zhu, Y Chai, L Jin, Y Ma, H Lu, Y Chen, W Feng - Scientific Reports, 2023 - nature.com
Lung adenocarcinoma (LUAD) remains an incurable disease with a poor prognosis. This
study aimed to explore neutrophil‑related genes (NRGs) and develop a prognostic signature …

Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma

F Rezagholizadeh, F Tajik, M Talebi, SR Taha… - Frontiers in …, 2024 - frontiersin.org
Introduction Pancreatic cancer is a truculent disease with limited treatment options and a
grim prognosis. Immunotherapy has shown promise in treating various types of cancer, but …

A noninvasive approach to evaluate tumor immune microenvironment and predict outcomes in hepatocellular carcinoma

J Wu, W Liu, X Qiu, J Li, K Song, S Shen, L Huo… - Phenomics, 2023 - Springer
It is widely recognized that tumor immune microenvironment (TIME) plays a crucial role in
tumor progression, metastasis, and therapeutic response. Despite several noninvasive …

Methylation-related genes involved in renal carcinoma progression

JM Zamora-Fuentes, E Hernández-Lemus… - Frontiers in …, 2023 - frontiersin.org
Renal carcinomas are a group of malignant tumors often originating in the cells lining the
small tubes in the kidney responsible for filtering waste from the blood and urine production …

FoxP3 Expression in Tumor-Infiltrating Lymphocytes as Potential Predictor of Response to Immune Checkpoint Inhibitors in Patients with Advanced Melanoma and …

P Grell, S Borilova, P Fabian, I Selingerova, D Novak… - Cancers, 2023 - mdpi.com
Simple Summary In the last decade, immunotherapy has revolutionized the treatment of
malignant melanoma and non-small cell lung cancer. Even though both tumor types have …