Oral delivery of hydrophobic flavonoids and their incorporation into functional foods: Opportunities and challenges

R Premathilaka, A Rashidinejad, M Golding, J Singh - Food Hydrocolloids, 2022 - Elsevier
Flavonoids have long been known for their healing powers in human ailments, with recent
trends seeing these natural bioactive components increasingly extended into nutraceuticals …

Morin as an imminent functional food ingredient: An update on its enhanced efficacy in the treatment and prevention of metabolic syndromes

K Thakur, YY Zhu, JY Feng, JG Zhang, F Hu… - Food & function, 2020 - pubs.rsc.org
Flavonoids represent polyphenolic plant secondary metabolites with a general structure of a
15-carbon skeleton comprising two phenyl rings and a heterocyclic ring. Over 5000 natural …

Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies

HM Campos, M da Costa, LK da Silva Moreira… - Toxicology, 2022 - Elsevier
Chronic exposure to aluminium (Al) can contribute to the progression of several neurological
and neurodegenerative diseases. Al is a metal that promotes oxidative damage leading to …

[HTML][HTML] Comparison of antioxidant properties of a conjugate of taxifolin with glyoxylic acid and selected flavonoids

VS Shubina, VI Kozina, YV Shatalin - Antioxidants, 2021 - mdpi.com
It is known that flavonoids can react with toxic carbonyl compounds in the process of the
storage, aging, and digestion of flavonoid-rich foods and beverages. However, the effect of …

Phytoestrogen coumestrol: Antioxidant capacity and its loading in albumin nanoparticles

G Montero, F Arriagada, G Günther, S Bollo… - International Journal of …, 2019 - Elsevier
Coumestrol is a polyphenol with promising therapeutic applications as phytoestrogen,
antioxidant and potential cancer chemoprevention agent. The presence of two hydroxyl …

[HTML][HTML] Morin flavonoid adsorbed on mesoporous silica, a novel antioxidant nanomaterial

F Arriagada, O Correa, G Günther, S Nonell, F Mura… - PloS one, 2016 - journals.plos.org
Morin (2´, 3, 4´, 5, 7-pentahydroxyflavone) is a flavonoid with several beneficial health
effects. However, its poor water solubility and it sensitivity to several environmental factors …

Flavone functionalized magnetic nanoparticles: A new fluorescent sensor for Cu2+ ions with nanomolar detection limit

LM de la Rosa-Romo, MT Oropeza-Guzmán… - Sensors and Actuators B …, 2016 - Elsevier
This paper presents the preparation and characterization of a new class of fluorescent core-
shell magnetic nanoparticles composed of a Fe 3 O 4 core, coated with amino-functionalized …

Potential use of nanocarriers with pentacyclic triterpenes in cancer treatments

K Valdés, J Morales, L Rodríguez, G Günther - Nanomedicine, 2016 - Taylor & Francis
Ursolic, oleanolic and betulinic acids are representative pentacyclic triterpenoids found in
various plants and fruits. Despite having marked antitumor potentials, the very poor water …

Nose-to-brain delivery of natural compounds for the treatment of central nervous system disorders

J Bicker, A Fortuna, G Alves… - Current Pharmaceutical …, 2020 - ingentaconnect.com
Background: Several natural compounds have demonstrated potential for the treatment of
central nervous system disorders such as ischemic cerebrovascular disease, glioblastoma …

Ellagic acid: A potent glyoxalase-I inhibitor with a unique scaffold

NA Al-Shar'i, QA Al-Balas, MA Hassan… - Acta …, 2021 - hrcak.srce.hr
Sažetak The glyoxalase system, particularly glyoxalase-I (GLO-I), has been approved as a
potential target for cancer treatment. In this study, a set of structurally diverse polyphenolic …