Thymoquinone and its therapeutic potentials
S Darakhshan, AB Pour, AH Colagar… - Pharmacological …, 2015 - Elsevier
Herbal medicine has attracted great attention in the recent years and is increasingly used as
alternatives to chemical drugs. Several lines of evidence support the positive impact of …
alternatives to chemical drugs. Several lines of evidence support the positive impact of …
Therapeutic potential and pharmaceutical development of thymoquinone: a multitargeted molecule of natural origin
Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-
benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known …
benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known …
Bax/Bcl-2 cascade is regulated by the EGFR pathway: therapeutic targeting of non-small cell lung cancer
Non-small cell lung carcinoma (NSCLC) comprises 80%–85% of lung cancer cases. EGFR
is involved in several cancer developments, including NSCLC. The EGFR pathway …
is involved in several cancer developments, including NSCLC. The EGFR pathway …
Thymoquinone: fifty years of success in the battle against cancer models
R Schneider-Stock, IH Fakhoury, AM Zaki… - Drug discovery today, 2014 - Elsevier
Highlights•This year marks 50 years since thymoquinone was isolated from black
seed.•Thymoquinone has had a long history of battling cancer in vitro and in …
seed.•Thymoquinone has had a long history of battling cancer in vitro and in …
Review on molecular and therapeutic potential of thymoquinone in cancer
S Banerjee, S Padhye, A Azmi, Z Wang… - Nutrition and …, 2010 - Taylor & Francis
Thymoquinone (TQ) is the predominant bioactive constituent present in black seed oil
(Nigella sativa) and has been tested for its efficacy against cancer. Here, we summarize the …
(Nigella sativa) and has been tested for its efficacy against cancer. Here, we summarize the …
Beneficial effects of thymoquinone on hepatic key enzymes in streptozotocin–nicotinamide induced diabetic rats
L Pari, C Sankaranarayanan - Life sciences, 2009 - Elsevier
AIMS: The present study was designed to evaluate the antihyperglycemic potential of
thymoquinone (TQ), major constituent of Nigella sativa seeds on the activities of key …
thymoquinone (TQ), major constituent of Nigella sativa seeds on the activities of key …
Protective effects of propolis and thymoquinone on development of atherosclerosis in cholesterol-fed rabbits
MA Nader, DS El-Agamy, GM Suddek - Archives of pharmacal research, 2010 - Springer
Hypercholesterolemia, cholesterol-enriched diet and oxidative stress have been shown to
increase serum total cholesterol (TC) and low density lipoprotein-cholesterol (LDL-C) levels …
increase serum total cholesterol (TC) and low density lipoprotein-cholesterol (LDL-C) levels …
Therapeutic implications of black seed and its constituent thymoquinone in the prevention of cancer through inactivation and activation of molecular pathways
The cancer is probably the most dreaded disease in both men and women and also major
health problem worldwide. Despite its high prevalence, the exact molecular mechanisms of …
health problem worldwide. Despite its high prevalence, the exact molecular mechanisms of …
[HTML][HTML] Black seed (Nigella sativa) and its constituent thymoquinone as an antidote or a protective agent against natural or chemical toxicities
Abstract Nigella sativa (N. sativa), which belongs to the botanical family of Ranunculaceae,
is a widely used medicinal plant all over the world. N. sativa seeds and oil have been used …
is a widely used medicinal plant all over the world. N. sativa seeds and oil have been used …
Protective effects of thymoquinone against methotrexate-induced testicular injury
Thymoquinone is the major active component derived from Nigella sativa. Methotrexate is a
folic acid antagonist widely used in clinic. Aim of this study was to investigate the possible …
folic acid antagonist widely used in clinic. Aim of this study was to investigate the possible …