Ozone (O3) is a natural, highly unstable atmospheric gas that rapidly decomposes to
oxygen. Although not being a radical molecule, O3 is a very strong oxidant and therefore it is …

Abstract Systems medicine is founded on a mechanism-based approach and identifies in
this way specific therapeutic targets. This approach has been applied for the transcription …

Objective: Unusual setting of medical care Background: Pneumonia caused by coronavirus
originated in Wuhan, China in late 2019 and has spread around the world, becoming a …

Background There is still no specific treatment strategies for COVID-19 other than supportive
management. Design A prospective case-control study determined by admittance to the …

Background Stroke, especially ischemic stroke (IS), has been a severe public health
problem around the world. However, the association between air pollution and ischemic …

In the last twenty years there has been a proliferation of articles on the therapeutic use of
ozone. As it is well-known, the term ozone therapy is very broad. It ranges from either …

Ozone therapy has been widely used to treat many skin diseases, including infections,
allergic dermatosis, and skin ulcers. However, its efficacy as a treatment for psoriasis is …

Background and purpose The data concerning the association between environmental
pollution and epilepsy attacks are limited. The aim of this study was to explore the …

Ozone (O3) is a reactive oxygen species (ROS) that can interact with cellular components
and cause oxidative stress. Following said logic, if O3 induces such a stressful milieu, how …

Valporic acid (VPA) has been implicated to have anti-inflammatory and anti-oxidant activities
in several ischemic/reperfusion (I/R) injury models. This study intended to evaluate whether …