Action of antimicrobial peptides against bacterial biofilms

M Yasir, MDP Willcox, D Dutta - Materials, 2018 - mdpi.com
Microbes are known to colonize surfaces and form biofilms. These biofilms are communities
of microbes encased in a self-produced matrix that often contains polysaccharides, DNA and …

Combination therapies for biofilm inhibition and eradication: a comparative review of laboratory and preclinical studies

S Hawas, AD Verderosa, M Totsika - Frontiers in cellular and infection …, 2022 - frontiersin.org
Microbial biofilms are becoming increasingly difficult to treat in the medical setting due to
their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are …

A series of MOF/Ce-based nanozymes with dual enzyme-like activity disrupting biofilms and hindering recolonization of bacteria

Z Liu, F Wang, J Ren, X Qu - Biomaterials, 2019 - Elsevier
Notorious bacterial biofilms are becoming severe threats to public health worldwide. As the
important component in biofilm extracellular polymeric substances (EPS), extracellular DNA …

Bacterial biofilm infections, their resistance to antibiotics therapy and current treatment strategies

A Singh, A Amod, P Pandey, P Bose… - Biomedical …, 2022 - iopscience.iop.org
Nearly 80% of human chronic infections are caused due to bacterial biofilm formation. This
is the most leading cause for failure of medical implants resulting in high morbidity and …

Pseudomonas aeruginosa: patogenicidad y resistencia antimicrobiana en la infección urinaria

VM Paz-Zarza, S Mangwani-Mordani… - Revista chilena de …, 2019 - SciELO Chile
Dentro de las infecciones nosocomiales más frecuentes asociadas a bacterias multi-
resistentes y de peor pronóstico, se encuentran las producidas por Pseudomonas …

Combination strategies to enhance the efficacy of antimicrobial peptides against bacterial biofilms

L Grassi, G Maisetta, S Esin, G Batoni - Frontiers in Microbiology, 2017 - frontiersin.org
The great clinical significance of biofilm-associated infections and their inherent
recalcitrance to antibiotic treatment urgently demand the development of novel antibiofilm …

An update on recent developments in the prevention and treatment of Staphylococcus aureus biofilms

MK Suresh, R Biswas, L Biswas - International Journal of Medical …, 2019 - Elsevier
Staphylococcus aureus (S. aureus) readily forms biofilms on prosthetic devices such as the
pacemakers, heart valves, orthopaedic implants, and indwelling catheters. Its biofilms are …

Therapeutic potential of antimicrobial peptides in polymicrobial biofilm-associated infections

G Batoni, G Maisetta, S Esin - International Journal of Molecular Sciences, 2021 - mdpi.com
It is widely recognized that many chronic infections of the human body have a polymicrobial
etiology. These include diabetic foot ulcer infections, lung infections in cystic fibrosis …

Synthetic peptides that form nanostructured micelles have potent antibiotic and antibiofilm activity against polymicrobial infections

S Chou, H Guo, FG Zingl, S Zhang… - Proceedings of the …, 2023 - National Acad Sciences
The emergence of multidrug-resistant bacterial pathogens is a growing threat to global
public health. Here, we report the development and characterization of a panel of nine …

Novel colistin-EDTA combination for successful eradication of colistin-resistant Klebsiella pneumoniae catheter-related biofilm infections

AMS Shein, DL Wannigama, PG Higgins, C Hurst… - Scientific reports, 2021 - nature.com
Abstract Development of an effective therapy to overcome colistin resistance in Klebsiella
pneumoniae, a common pathogen causing catheter-related biofilm infections in vascular …