Detection of tuberculosis by the analysis of exhaled breath particles with high-resolution mass spectrometry

D Chen, WA Bryden, R Wood - Scientific reports, 2020 - nature.com
Tuberculosis remains a global health threat killing over 1 million people per year. Current
sputum-based diagnostics are specific but lack sensitivity resulting in treatment of many …

Boron-doped carbon nanowalls for fast and direct detection of cytochrome C and ricin by matrix-free laser desorption/ionization mass spectrometry

IS Hosu, M Sobaszek, M Ficek, R Bogdanowicz… - Talanta, 2023 - Elsevier
Detecting proteins via surface assisted laser desorption/ionization mass spectrometry
(SALDI-MS) method is still highly challenging, and only few examples of nanomaterials have …

Direct Acetonitrile-Assisted Trypsin Digestion Method Combined with LC–MS/MS-Targeted Peptide Analysis for Unambiguous Identification of Intact Ricin

CC Liu, LH Liang, Y Yang, HL Yu, L Yan… - Journal of Proteome …, 2020 - ACS Publications
Ricin is a type II ribosome-inactivating protein toxin consisting of A and B chains linked by
one interchain disulfide bond. Because of its high toxicity depending on both chains …

Rapid differential detection of abrin isoforms by an acetonitrile-and ultrasound-assisted on-bead trypsin digestion coupled with LC-MS/MS analysis

LH Liang, Y Yang, S Geng, X Cheng, HL Yu, CC Liu… - Toxins, 2021 - mdpi.com
The high toxic abrin from the plant Abrus precatorius is a type II ribosome-inactivating
protein toxin with a human lethal dose of 0.1–1.0 µg/kg body weight. Due to its high toxicity …

MALDI-TOF mass spectrometric detection of SARS-CoV-2 using cellulose sulfate Ester enrichment and hot acid treatment

D Chen, WA Bryden, C Fenselau… - Journal of Proteome …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the ongoing
coronavirus disease 2019 (COVID-19) pandemic. Here we report a novel strategy for the …

A self-driven microfluidic chip for ricin and abrin detection

X Bai, C Hu, L Chen, J Wang, Y Li, W Wan, Z Jin, Y Li… - Sensors, 2022 - mdpi.com
Ricin and abrin are phytotoxins that can be easily used as biowarfare and bioterrorism
agents. Therefore, developing a rapid detection method for both toxins is of great …

Microwave supported hydrolysis prepares Bacillus spores for proteomic analysis

D Chen, WA Bryden, C Fenselau - International journal of mass …, 2019 - Elsevier
Rapid identification of Bacillus spores in the environment has depended primarily on a
family of small acid soluble proteins (SASPs) as biomarkers. However, SASP sequences …

Highly toxic type Ⅱ ribosome-inactivating proteins ricin and abrin and their detection methods: a review

L Liang, J Xia, C Liu, S Liu - Se pu= Chinese Journal of …, 2021 - europepmc.org
Abstract Ⅱ 型核糖体失活蛋白 (RIPs) 是一类重要的蛋白毒素, 该类毒素大都具有一对二硫键
连接的 AB 链结构特征, B 链具有半乳糖结合特性, 能够与真核细胞膜表面受体特异性结合 …

[HTML][HTML] 剧毒性Ⅱ 型核糖体失活蛋白蓖麻毒素和相思子毒素的检测鉴定方法研究进展

L LIANG, XIA Junmei, LIU Changcai… - Chinese Journal of …, 2021 - ncbi.nlm.nih.gov
Abstract Ⅱ 型核糖体失活蛋白(RIPs) 是一类重要的蛋白毒素, 该类毒素大都具有一对二硫键
连接的AB 链结构特征, B 链具有半乳糖结合特性, 能够与真核细胞膜表面受体特异性结合 …

MALDI Mass Spectrometry Imaging in the Forensic Arena

R Bradshaw, S Francese - 2021 - books.rsc.org
While still niche, the application of Matrix Assisted Laser Desorption Ionization–Mass
Spectrometry Imaging (MALDI-MSI) in the forensic arena is exciting due to interesting …