Colorectal cancer (CRC) is one of the most common cancers worldwide. Current therapies
such as surgery, chemotherapy, and radiotherapy encounter obstacles in preventing …

Cancer vaccines and immune checkpoint inhibitors (ICIs) function at different stages of the
cancer immune cycle due to their distinct mechanisms of action. Therapeutic cancer …

Listeria monocytogenes is a foodborne intracellular bacterial pathogen leading to human
listeriosis. Despite a high mortality rate and increasing antibiotic resistance no clinically …

Cancer receives enduring international attention due to its extremely high morbidity and
mortality. Immunotherapy, which is generally expected to overcome the limits of traditional …

Introduction Colorectal cancer (CRC) is a devastating disease that affects millions of people
worldwide. Recent research has highlighted the crucial role of the guanylate cyclase-C (GC …

There are increasing incidences and mortality rates for colorectal cancer in the world. It is
common for chemotherapy and radiation given to patients with colorectal cancer to cause …

Strategies to augment immunity to self/neoantigens expressed by cancers are urgently
needed to expand the proportion of patients benefiting from immunotherapy, particularly for …

Colorectal cancer remains a major cause of mortality in the USA, despite advances in
prevention and screening. Existing therapies focus primarily on generic treatment such as …

The role of minor histocompatibility antigens (mHAs) in mediating graft versus leukemia and
graft versus host disease (GvHD) following allogeneic hematopoietic cell transplantation …

It has long been known that oncolytic viruses wield their therapeutic capability by priming an
inflammatory state within the tumor and activating the tumor immune microenvironment …