Cardiac surgery is associated with perioperative blood loss and a high risk of allogeneic
blood transfusion. Patient blood management (PBM) in cardiac surgery contributes to the …

Background Concerns regarding the safety of transfused blood have led to the development
of a range of interventions to minimise blood loss during major surgery. Anti‐fibrinolytic …

Document Reviewers: Moritz WV Wyler von Ballmoos (USA), Mate Petricevic (Croatia), Arie
Pieter Kappetein (Netherlands), Miguel Sousa-Uva (Portugal), Georg Trummer (Germany) …

Background Antifibrinolytic agents are commonly used during cardiac surgery to minimize
bleeding and to reduce exposure to blood products. We sought to determine whether …

BACKGROUND: Cerebral deoxygenation is associated with various adverse systemic
outcomes. We hypothesized, by using the brain as an index organ, that interventions to …

BACKGROUND: A minority of patients having cardiac procedures (15% to 20%) consume
more than 80% of the blood products transfused at operation. Blood must be viewed as a …

Background The majority of patients undergoing surgical treatment for ST-elevation
myocardial infarction receive antifibrinolytic therapy to limit blood loss. This approach …

Stroke is one of the most feared complications of surgery. This article reviews the
pathophysiology of perioperative stroke, explains risk-factor stratification, and provides …

Thrombosis has long been recognized as a potentially lifethreatening complication in
children with congenital heart disease (CHD), children with acquired heart disease, and in …

The most common medical cause of major blood loss is surgery, particularly cardiovascular
procedures, liver transplantation and hepatic resection, and major orthopedic procedures …