During lung cancer operations a rapid and reliable assessment of tumor tissue can reduce
operation time and potentially improve patient outcomes. We show that third harmonic …

Distinguishing tumors from normal brain cells is important but challenging in glioma surgery
due to the lack of clear interfaces between the two. The ability of label‐free third harmonic …

Real‐time assessment of excised tissue may help to improve surgical results in breast tumor
surgeries. Here, as a step towards this purpose, the potential of second and third harmonic …

Collagen fibers in biological tissues have a complex 3D organization containing rich
information linked to tissue mechanical properties and are affected by mutations that lead to …

In the current clinical care practice, Gleason grading system is one of the most powerful
prognostic predictors for prostate cancer (PCa). The grading system is based on the …

We use second-harmonic generation (SHG) microscopy to quantitatively characterize
collagen fiber crimping in the posterior cruciate ligament (PCL). The obtained SHG images …

We present the results of polarimetric analysis of collagen on varying pathologies of breast
tissues using second-harmonic patterned polarization-analyzed reflection confocal …

Reflective objectives (ROs) mitigate chromatic aberration across a broad wavelength range.
Yet, a systematic performance characterisation of ROs has not been done. In this paper, we …

Multiphoton microscopy provides a suitable technique for imaging biological tissues with
submicrometer resolution. Usually a Gaussian beam (GB) is used for illumination, leading to …

Environmental-scanning electron microscopy (ESEM) is routinely applied to various
biological samples due to its ability to maintain a wet environment while imaging; moreover …