Acute pancreatitis: diagnosis and treatment

P Szatmary, T Grammatikopoulos, W Cai, W Huang… - Drugs, 2022 - Springer
Acute pancreatitis is a common indication for hospital admission, increasing in incidence,
including in children, pregnancy and the elderly. Moderately severe acute pancreatitis with …

Diagnosis and management of chronic pancreatitis: a review

VK Singh, D Yadav, PK Garg - Jama, 2019 - jamanetwork.com
Importance Chronic pancreatitis (CP) is a chronic inflammatory and fibrotic disease of the
pancreas with a prevalence of 42 to 73 per 100 000 adults in the United States …

Diabetes, pancreatogenic diabetes, and pancreatic cancer

DK Andersen, M Korc, GM Petersen, G Eibl, D Li… - Diabetes, 2017 - Am Diabetes Assoc
The relationships between diabetes and pancreatic ductal adenocarcinoma (PDAC) are
complex. Longstanding type 2 diabetes (T2DM) is a risk factor for pancreatic cancer, but …

Chronic pancreatitis

J Kleeff, DC Whitcomb, T Shimosegawa… - Nature reviews Disease …, 2017 - nature.com
Chronic pancreatitis is defined as a pathological fibro-inflammatory syndrome of the
pancreas in individuals with genetic, environmental and/or other risk factors who develop …

Genetics, cell biology, and pathophysiology of pancreatitis

J Mayerle, M Sendler, E Hegyi, G Beyer, MM Lerch… - Gastroenterology, 2019 - Elsevier
Since the discovery of the first trypsinogen mutation in families with hereditary pancreatitis,
pancreatic genetics has made rapid progress. The identification of mutations in genes …

Chronic pancreatitis

S Majumder, ST Chari - The Lancet, 2016 - thelancet.com
Chronic pancreatitis describes a wide spectrum of fibro-inflammatory disorders of the
exocrine pancreas that includes calcifying, obstructive, and steroid-responsive forms. Use of …

Frequency of progression from acute to chronic pancreatitis and risk factors: a meta-analysis

SJ Sankaran, AY Xiao, LM Wu, JA Windsor… - Gastroenterology, 2015 - Elsevier
Background & Aim Acute pancreatitis (AP) and chronic pancreatitis (CP) traditionally have
been thought to be distinct diseases, but there is evidence that AP can progress to CP. Little …

[HTML][HTML] Arizona study of aging and neurodegenerative disorders and brain and body donation program

TG Beach, CH Adler, LI Sue, G Serrano… - … : official journal of the …, 2015 - ncbi.nlm.nih.gov
Abstract The Brain and Body Donation Program (BBDP) at Banner Sun Health Research
Institute (http://www. brainandbodydonationprogram. org) started in 1987 with brain-only …

[HTML][HTML] Cathepsin B-mediated activation of trypsinogen in endocytosing macrophages increases severity of pancreatitis in mice

M Sendler, FU Weiss, J Golchert, G Homuth… - Gastroenterology, 2018 - Elsevier
Background & Aims Acute pancreatitis is characterized by premature intracellular activation
of digestive proteases within pancreatic acini and a consecutive systemic inflammatory …

Acute pancreatitis: a multifaceted set of organelle and cellular interactions

A Habtezion, AS Gukovskaya, SJ Pandol - Gastroenterology, 2019 - Elsevier
Acute pancreatitis is an inflammatory disorder of the exocrine pancreas associated with
tissue injury and necrosis. The disease can be mild, involving only the pancreas, and …