Mast cells (MCs) are versatile effector cells of the immune system, characterized by a large
content of secretory granules containing a variety of inflammatory mediators. They are …

Mast cell activation disease (MCAD) is a term referring to a heterogeneous group of
disorders characterized by aberrant release of variable subsets of mast cell (MC) mediators …

Inhibitory signaling during natural killer (NK) cell education translates into increased
responsiveness to activation; however, the intracellular mechanism for functional tuning by …

Mast cell (MC) disease has long been thought to be just the rare disease of mastocytosis (in
various forms, principally cutaneous and systemic), with aberrant MC mediator release at …

Summary Hybrid Th1/Tfh cells (IFN-γ+ IL-21+ CXCR5+) predominate in response to several
persistent infections. In Plasmodium chabaudi infection, IFN-γ+ T cells control parasitemia …

Mefloquine is a quinoline-based compound widely used as an antimalarial drug, particularly
in chemoprophylaxis. Although decades of research have identified various aspects of …

Despite the efficacy of BCR-ABL tyrosine kinase inhibitors (TKIs) in chronic phase-chronic
myeloid leukemia, the management of blast phase-chronic myeloid leukemia (BP-CML) …

Background: Platelet-rich plasma (PRP) is an autologous concentrated preparation of
platelets characterized by lymphangiogenetic and tissue-repairing effects. Although PRP …

Malaria, a mosquito-borne infectious disease, is a severe health problem worldwide. As
reported, some anti-malarial drugs with anti-parasitic properties also block mast cells (MCs) …

Mast cells are multifunctional immune cells scattered in tissues near blood vessels and
mucosal surfaces where they mediate important reactions against parasites and contribute …