Temperature-responsive smart nanocarriers for delivery of therapeutic agents: applications and recent advances
M Karimi, P Sahandi Zangabad… - … applied materials & …, 2016 - ACS Publications
Smart drug delivery systems (DDSs) have attracted the attention of many scientists, as
carriers that can be stimulated by changes in environmental parameters such as …
carriers that can be stimulated by changes in environmental parameters such as …
Injectable hydrogels for cardiac tissue engineering
In light of the limited efficacy of current treatments for cardiac regeneration, tissue
engineering approaches have been explored for their potential to provide mechanical …
engineering approaches have been explored for their potential to provide mechanical …
Heparin-based and heparin-inspired hydrogels: size-effect, gelation and biomedical applications
Heparin is the highest negatively charged biomolecule, which is a polysaccharide belonging
to the glycosaminoglycan family, and its role as a regulator of various proteins, cells and …
to the glycosaminoglycan family, and its role as a regulator of various proteins, cells and …
Gold nanoparticle-functionalized reverse thermal gel for tissue engineering applications
Utilizing polymers in cardiac tissue engineering holds promise for restoring function to the
heart following myocardial infarction, which is associated with grave morbidity and mortality …
heart following myocardial infarction, which is associated with grave morbidity and mortality …
Injectable carbon nanotube-functionalized reverse thermal gel promotes cardiomyocytes survival and maturation
The ability of the adult heart to regenerate cardiomyocytes (CMs) lost after injury is limited,
generating interest in developing efficient cell-based transplantation therapies. Rigid carbon …
generating interest in developing efficient cell-based transplantation therapies. Rigid carbon …
Injectable polymeric delivery system for spatiotemporal and sequential release of therapeutic proteins to promote therapeutic angiogenesis and reduce inflammation
AJ Rocker, DJ Lee, R Shandas… - ACS biomaterials science …, 2020 - ACS Publications
Myocardial infarction (MI) causes cardiac cell death, induces persistent inflammatory
responses, and generates harmful pathological remodeling, which leads to heart failure …
responses, and generates harmful pathological remodeling, which leads to heart failure …
Biomimetic polymers for cardiac tissue engineering
B Peña, V Martinelli, M Jeong, S Bosi… - …, 2016 - ACS Publications
Heart failure is a morbid disorder characterized by progressive cardiomyocyte (CM)
dysfunction and death. Interest in cell-based therapies is growing, but sustainability of …
dysfunction and death. Interest in cell-based therapies is growing, but sustainability of …
An injectable sulfonated reversible thermal gel for therapeutic angiogenesis to protect cardiac function after a myocardial infarction
DJ Lee, MA Cavasin, AJ Rocker, DE Soranno… - Journal of biological …, 2019 - Springer
Background Cardiovascular disease and myocardial infarction are associated with high
mortality and morbidity and a more effective treatment remains a major clinical need. The …
mortality and morbidity and a more effective treatment remains a major clinical need. The …
Injectable neurotrophic factor delivery system supporting retinal ganglion cell survival and regeneration following optic nerve crush
MR Laughter, JR Bardill, DA Ammar… - ACS biomaterials …, 2018 - ACS Publications
In general, neurons belonging to the central nervous system (CNS), such as retinal ganglion
cells (RGCs), do not regenerate. Due to this, strategies have emerged aimed at protecting …
cells (RGCs), do not regenerate. Due to this, strategies have emerged aimed at protecting …
Highly hemo-compatible, mechanically strong, and conductive dual cross-linked polymer hydrogels
A new class of hydrogels distinguished by electro-conductivity and high hemo-compatibility,
which resemble biological tissues, are promising candidates for a plethora of biomedical …
which resemble biological tissues, are promising candidates for a plethora of biomedical …