Silymarin: a review on paving the way towards promising pharmacological agent

MN Akhtar, R Saeed, F Saeed, A Asghar… - … Journal of Food …, 2023 - Taylor & Francis
Advancements in the field of research and development have paved toward the use of
herbal agents to cure and control health maladies. Milk thistle (Silybum marianum L.) is one …

[HTML][HTML] The interplay of arsenic, silymarin, and NF-ĸB pathway in male reproductive toxicity: A review

AG Mukherjee, AV Gopalakrishnan - Ecotoxicology and Environmental …, 2023 - Elsevier
Arsenic toxicity is one of the most trending reasons for several malfunctions, particularly
reproductive toxicity. The exact mechanism of arsenic poisoning is a big question mark …

Exogenous factors affecting the functional integrity of male reproduction

F Tirpák, H Greifová, N Lukáč, R Stawarz, P Massányi - Life, 2021 - mdpi.com
Natural processes along with increased industrial production and the irresponsible behavior
of mankind have resulted in environmental pollution. Environmental pollutants can be …

The roles of MicroRNAs in cadmium toxicity and in the protection offered by plant food-derived dietary phenolic bioactive substances against cadmium-induced toxicity

R Hao, F Li, D Sun-Waterhouse, D Li - Food Chemistry, 2024 - Elsevier
Cadmium, a harmful food contaminant, poses severe health risks. There are ongoing efforts
to reduce cadmium pollution and alleviate its toxicity, including plant-based dietary …

Impacts of cadmium on male fertility: Lessons learnt so far

EJ Ikokide, AA Oyagbemi, MO Oyeyemi - Andrologia, 2022 - Wiley Online Library
Cadmium (Cd) is one of the most dangerous heavy metals in the world. Globally, toxicities
associated with cadmium and its attendant negative impact on humans and animals cannot …

Quercetin supplementation alleviates cadmium induced genotoxicity-mediated apoptosis in caprine testicular cells

H Panchal, JK Bhardwaj - Biological trace element research, 2024 - Springer
Being a common environmental pollutant, cadmium causes detrimental health effects,
including testicular injury. Herein, we document the ameliorative potential of quercetin, a …

Silymarin modulates cadmium‐induced oxidative stress in human spermatozoa

T Etemadi, HR Momeni, N Darbandi, MH Abnosi - Andrologia, 2022 - Wiley Online Library
Environmental pollutants such as cadmium can negatively affect sperm parameters and
decrease male fertility by inducing oxidative stress. Antioxidants are considered a useful …

Seminal trace elements and their relationship with sperm parameters

S Karabulut, S Korkmaz, E Güneş, E Kabil, İ Keskin… - Andrologia, 2022 - Wiley Online Library
Male reproductive problems may derive from many reasons including the environmental
toxicants which may either intaken by occupational exposure, nutrition or bad air quality. The …

Exosomes are involved in total body irradiation-induced intestinal injury in mice

H Li, M Jiang, S Zhao, S Zhang, L Lu, X He… - Acta pharmacologica …, 2021 - nature.com
Ionizing radiation-induced intestinal injury is a catastrophic complication in patients
receiving radiotherapy. Circulating exosomes from patients undergoing radiotherapy can …

Comparative efficacy of silibinin and nano-silibinin on lead poisoning in Male Wistar rats

M Mohammadi, S Ariafar, E Talebi-Ghane, S Afzali - Toxicology, 2022 - Elsevier
Lead (Pb) is an environmental neurotoxin that can lead to toxicity. It has shown that tissues
can be exposed to oxidative stress in lead poisoning. Since silymarin is a natural agent with …