[HTML][HTML] Role of oxidative stress in the pathogenesis of non-alcoholic fatty liver disease: implications for prevention and therapy
JC Arroyave-Ospina, Z Wu, Y Geng, H Moshage - Antioxidants, 2021 - mdpi.com
Oxidative stress (OxS) is considered a major factor in the pathophysiology of inflammatory
chronic liver diseases, including non-alcoholic liver disease (NAFLD). Chronic impairment of …
chronic liver diseases, including non-alcoholic liver disease (NAFLD). Chronic impairment of …
AMP-activated protein kinase: An energy sensor and survival mechanism in the reinstatement of metabolic homeostasis
Cells are programmed to favorably respond towards the nutrient availability by adapting
their metabolism to meet energy demands. AMP-activated protein kinase (AMPK) is a highly …
their metabolism to meet energy demands. AMP-activated protein kinase (AMPK) is a highly …
[HTML][HTML] Hepatocyte-specific suppression of ANGPTL4 improves obesity-associated diabetes and mitigates atherosclerosis in mice
Hepatic uptake and biosynthesis of fatty acids (FAs), as well as the partitioning of FAs into
oxidative, storage, and secretory pathways, are tightly regulated processes. Dysregulation of …
oxidative, storage, and secretory pathways, are tightly regulated processes. Dysregulation of …
[HTML][HTML] Diosgenin ameliorates palmitic acid-induced lipid accumulation via AMPK/ACC/CPT-1A and SREBP-1c/FAS signaling pathways in LO2 cells
K Fang, F Wu, G Chen, H Dong, J Li, Y Zhao… - … and Alternative Medicine, 2019 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver
disease and is characterized by excessive hepatic lipid accumulation. Many studies have …
disease and is characterized by excessive hepatic lipid accumulation. Many studies have …
[HTML][HTML] Mitochondrial oxidative function in NAFLD: Friend or foe?
Background Mitochondrial oxidative function plays a key role in the development of non-
alcoholic fatty liver disease (NAFLD) and insulin resistance (IR). Recent studies reported …
alcoholic fatty liver disease (NAFLD) and insulin resistance (IR). Recent studies reported …
[HTML][HTML] Targeting hepatic kisspeptin receptor ameliorates nonalcoholic fatty liver disease in a mouse model
S Guzman, M Dragan, H Kwon… - The Journal of …, 2022 - Am Soc Clin Investig
Nonalcoholic fatty liver disease (NAFLD), the most common liver disease, has become a
silent worldwide pandemic. The incidence of NAFLD correlates with the rise in obesity, type …
silent worldwide pandemic. The incidence of NAFLD correlates with the rise in obesity, type …
[HTML][HTML] Curcumin analog CUR5–8 ameliorates nonalcoholic fatty liver disease in mice with high-fat diet-induced obesity
ES Lee, MH Kwon, HM Kim, HB Woo, CM Ahn… - Metabolism, 2020 - Elsevier
Objective Nonalcoholic fatty liver disease (NAFLD) occurs when excess fat storage in the
liver and it is strongly linked with metabolic syndrome including obesity, insulin resistance …
liver and it is strongly linked with metabolic syndrome including obesity, insulin resistance …
Polystyrene nanoplastics induce lipid metabolism disorder and alter fatty acid composition in the hepatopancreas of Pacific whiteleg shrimp (Litopenaeus vannamei)
Y Li, Y Ye, N Rihan, B Zhu, Q Jiang, X Liu… - Science of the Total …, 2024 - Elsevier
The impact of nanoplastics (NPs) on environmental pollution and aquatic organisms has
gradually attracted attention, but there are relatively few reports of the effects of NPs on the …
gradually attracted attention, but there are relatively few reports of the effects of NPs on the …
[HTML][HTML] Non-Alcoholic Fatty Liver Disease or Type 2 Diabetes Mellitus—The Chicken or the Egg Dilemma
M Kosmalski, A Śliwińska, J Drzewoski - Biomedicines, 2023 - mdpi.com
In clinical practice, we often deal with patients who suffer from non-alcoholic fatty liver
disease (NAFLD) concurrent with type 2 diabetes mellitus (T2DM). The etiopathogenesis of …
disease (NAFLD) concurrent with type 2 diabetes mellitus (T2DM). The etiopathogenesis of …
[HTML][HTML] Oxidative stress in non-alcoholic fatty liver disease
C Smirne, E Croce, D Di Benedetto, V Cantaluppi… - Livers, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a challenging disease caused by multiple
factors, which may partly explain why it still remains an orphan of adequate therapies. This …
factors, which may partly explain why it still remains an orphan of adequate therapies. This …