End-stage organ failure can result from various preexisting conditions and occurs in patients
of all ages, and organ transplantation remains its only treatment. In recent years, extensive …

Islet transplantation (IT) is now a robust treatment for selected patients with type 1 diabetes
suffering from recurrent hypoglycemia and impaired awareness of hypoglycemia. A global …

Сахарный диабет как 1-го, так и 2-го типа характеризуется прогрессирующей потерей
массы β-клеток, что приводит к нарушению гомеостаза глюкозы. Оптимальной …

Diabetes of both type 1 and type 2 is characterized by a progressive loss of β-cell mass,
which contributes to the disruption of glucose homeostasis. The optimal antidiabetic therapy …

For the advancement of porcine xenotransplantation for clinical use in type 1 diabetes
mellitus, the concerns of a sustainable and safe digestion enzyme blend must be overcome …

Diabetes is a major challenge to healthcare providers globally, with significant human and
financial costs. Type 1 diabetes is expected to effect more than a million people …

Islet cell transplantation (IT) is a proven therapy in preventing severe hypoglycemia and
restoring insulin independence for the subgroups of patients with type 1 diabetes and …

Insulin replacement therapy is the mainstay treatment option for type 1 diabetes; however,
when this fails to adequately maintain glucose homeostasis, islet transplantation can …

Efficient and consistent cryopreservation of human islets would be a useful tool in
generating islet biobanks for transplantation and research uses. However, current islet …

For the advancement of porcine xenotransplantation for clinical use in type 1 diabetes
mellitus, the concerns of a sustainable and safe digestion enzyme blend must be overcome …