The human cerebral cortex is vastly expanded relative to other primates and
disproportionately occupied by distributed association regions. Here we offer a hypothesis …

Comparative neuroimaging can identify unique features of the human brain and teach us
about human brain evolution. Comparisons with chimpanzees, our closest living primate …

The human cortex comprises diverse cell types that emerge from an initially uniform
neuroepithelium that gives rise to radial glia, the neural stem cells of the cortex. To …

Direct comparisons of human and non-human primate brains can reveal molecular
pathways underlying remarkable specializations of the human brain. However, chimpanzee …

Without cesarean delivery, obstructed labor can result in maternal and fetal injuries or even
death given a disproportion in size between the fetus and the maternal birth canal. The …

What evolutionary events led to the emergence of human cognition? Although the genetic
differences separating modern humans from both non-human primates (for example …

It has been suggested that highly social mammals, such as naked mole rats and humans,
are long-lived due to neoteny (the prolongation of youth). In both species, aging cannot …

Humans and chimpanzees last shared a common ancestor about 5 to 6 million years ago.
Single-nucleotide substitutions occur at a mean rate of 1.23% between copies of the human …

Humans have a prolonged childhood, which begins with an immature developmental state
at birth. We take care of these helpless infants through a variety of cultural adaptations …

The lipidome is currently understudied but fundamental to life. Within the brain, little is
known about cell-type lipid heterogeneity, and even less is known about cell-to-cell lipid …