Abstract Organs-on-chips (OoCs) are systems containing engineered or natural miniature
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …

Many new techniques and materials have been applied to microfluidic systems in the past
decade, and integrated microfluidic chips have become powerful platforms for realizing …

Our understanding of diabetes mellitus has benefited from a combination of clinical
investigations and work in model organisms and cell lines. Organoid models for a wide …

Arthritis affects millions of people worldwide. With only a few disease-modifying drugs
available for treatment of rheumatoid arthritis and none for osteoarthritis, a clear need exists …

The potential impact of microplastics (MPs) on health has caused great concern, and a
toxicology platform that realistically reproduces the system behaviour is urgently needed to …

Obesity and its numerous adverse health consequences have taken on global, pandemic
proportions. White adipose tissue (WAT)–a key contributor in many metabolic diseases …

The expeditious advancement in the organ on chip technology provided a phase change to
the conventional in vitro tests used to evaluate absorption, distribution, metabolism …

An accurate in vitro model of human adipose tissue could assist in the study of adipocyte
function and allow for better tools for screening new therapeutic compounds. Cell culture …

Diabetes mellitus (DM) is a very serious disease, the incidence of which has been
increasing worldwide. The beginning of diabetic research can be traced back to the 17th …

Metabolic diseases have been a major public health issue and a clinical challenge
worldwide. Dysfunction of metabolic homeostasis is linked to the onset of various diseases …