Abstract Development of state-of-the-art assays for sensitive and specific detection of
disease biomarkers has received significant interest for early detection and prevention of …

Alzheimer's disease (AD) is a chronic disease amongst people aged 65 and older.
Increasing evidence has illustrated that early diagnosis holds the key to effective treatment …

The discipline of neurotheranostics was forged to improve diagnostic and therapeutic
clinical outcomes for neurological disorders. Research was facilitated, in largest measure …

Nanotechnology is an important branch of science in therapies known as “nanomedicine”
and is the junction of various fields such as material science, chemistry, biology, physics …

By virtue of their small size, nanomaterials can cross the blood-brain barrier and, when
modified to target specific cells or regions, can achieve high bioavailability at the intended …

Alzheimer's disease affects millions of people worldwide and this figure is continuously
increasing. Currently, there is no resolutive cure for this disorder, but a valid contribution …

Alzheimer's disease, Parkinson's disease and stroke are the most common CNS diseases,
all characterized by progressive cellular dysfunction and death in specific areas of the …

The effectiveness of noninvasive treatment for neurological disease is generally limited by
the poor entry of therapeutic agents into the central nervous system (CNS). Most CNS drugs …

The failure of therapeutic treatment of Alzheimer's disease (AD) patients can be related to
the late onset of symptoms and, consequently, to a delayed pharmacological aid to …

Immuno-polymerase chain reaction (I-PCR) assay with advantages of both enzyme-linked
immunosorbent assay (ELISA) and PCR exhibits several-fold enhanced sensitivity in …