Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies
KM Kennedy, MC de Goffau, ME Perez-Muñoz… - Nature, 2023 - nature.com
Whether the human fetus and the prenatal intrauterine environment (amniotic fluid and
placenta) are stably colonized by microbial communities in a healthy pregnancy remains a …
placenta) are stably colonized by microbial communities in a healthy pregnancy remains a …
[HTML][HTML] The dynamic lung microbiome in health and disease
JG Natalini, S Singh, LN Segal - Nature Reviews Microbiology, 2023 - nature.com
New methods and technologies within the field of lung biology are beginning to shed new
light into the microbial world of the respiratory tract. Long considered to be a sterile …
light into the microbial world of the respiratory tract. Long considered to be a sterile …
[HTML][HTML] Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer
A Fu, B Yao, T Dong, Y Chen, J Yao, Y Liu, H Li, H Bai… - Cell, 2022 - cell.com
Tumor-resident intracellular microbiota is an emerging tumor component that has been
documented for a variety of cancer types with unclear biological functions. Here, we …
documented for a variety of cancer types with unclear biological functions. Here, we …
[HTML][HTML] The human virome: assembly, composition and host interactions
G Liang, FD Bushman - Nature Reviews Microbiology, 2021 - nature.com
The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …
known is the fact that the human body also hosts vast numbers of different viruses …
[HTML][HTML] A faecal microbiota signature with high specificity for pancreatic cancer
Background Recent evidence suggests a role for the microbiome in pancreatic ductal
adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and …
adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and …
[HTML][HTML] Metagenomics-enabled microbial surveillance
KKK Ko, KR Chng, N Nagarajan - Nature Microbiology, 2022 - nature.com
Lessons learnt from the COVID-19 pandemic include increased awareness of the potential
for zoonoses and emerging infectious diseases that can adversely affect human health …
for zoonoses and emerging infectious diseases that can adversely affect human health …
[HTML][HTML] Interaction between microbiota and immunity in health and disease
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …
development and function includes multifold interactions in homeostasis and disease. The …
The human tumor microbiome is composed of tumor type–specific intracellular bacteria
Bacteria were first detected in human tumors more than 100 years ago, but the
characterization of the tumor microbiome has remained challenging because of its low …
characterization of the tumor microbiome has remained challenging because of its low …
Microbiome analyses of blood and tissues suggest cancer diagnostic approach
Systematic characterization of the cancer microbiome provides the opportunity to develop
techniques that exploit non-human, microorganism-derived molecules in the diagnosis of a …
techniques that exploit non-human, microorganism-derived molecules in the diagnosis of a …
BlobToolKit–interactive quality assessment of genome assemblies
R Challis, E Richards, J Rajan… - G3: Genes …, 2020 - academic.oup.com
Reconstruction of target genomes from sequence data produced by instruments that are
agnostic as to the species-of-origin may be confounded by contaminant DNA. Whether …
agnostic as to the species-of-origin may be confounded by contaminant DNA. Whether …