Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

KM Kennedy, MC de Goffau, ME Perez-Muñoz… - Nature, 2023 - nature.com
Whether the human fetus and the prenatal intrauterine environment (amniotic fluid and
placenta) are stably colonized by microbial communities in a healthy pregnancy remains a …

[HTML][HTML] The dynamic lung microbiome in health and disease

JG Natalini, S Singh, LN Segal - Nature Reviews Microbiology, 2023 - nature.com
New methods and technologies within the field of lung biology are beginning to shed new
light into the microbial world of the respiratory tract. Long considered to be a sterile …

[HTML][HTML] Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer

A Fu, B Yao, T Dong, Y Chen, J Yao, Y Liu, H Li, H Bai… - Cell, 2022 - cell.com
Tumor-resident intracellular microbiota is an emerging tumor component that has been
documented for a variety of cancer types with unclear biological functions. Here, we …

[HTML][HTML] The human virome: assembly, composition and host interactions

G Liang, FD Bushman - Nature Reviews Microbiology, 2021 - nature.com
The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …

[HTML][HTML] A faecal microbiota signature with high specificity for pancreatic cancer

E Kartal, TSB Schmidt, E Molina-Montes… - Gut, 2022 - gut.bmj.com
Background Recent evidence suggests a role for the microbiome in pancreatic ductal
adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and …

[HTML][HTML] Metagenomics-enabled microbial surveillance

KKK Ko, KR Chng, N Nagarajan - Nature Microbiology, 2022 - nature.com
Lessons learnt from the COVID-19 pandemic include increased awareness of the potential
for zoonoses and emerging infectious diseases that can adversely affect human health …

[HTML][HTML] Interaction between microbiota and immunity in health and disease

D Zheng, T Liwinski, E Elinav - Cell research, 2020 - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

D Nejman, I Livyatan, G Fuks, N Gavert, Y Zwang… - Science, 2020 - science.org
Bacteria were first detected in human tumors more than 100 years ago, but the
characterization of the tumor microbiome has remained challenging because of its low …

Microbiome analyses of blood and tissues suggest cancer diagnostic approach

GD Poore, E Kopylova, Q Zhu, C Carpenter… - Nature, 2020 - nature.com
Systematic characterization of the cancer microbiome provides the opportunity to develop
techniques that exploit non-human, microorganism-derived molecules in the diagnosis of a …

BlobToolKit–interactive quality assessment of genome assemblies

R Challis, E Richards, J Rajan… - G3: Genes …, 2020 - academic.oup.com
Reconstruction of target genomes from sequence data produced by instruments that are
agnostic as to the species-of-origin may be confounded by contaminant DNA. Whether …