[HTML][HTML] Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's disease

SF Kazim, K Iqbal - Molecular neurodegeneration, 2016 - Springer
Alzheimer's disease (AD) is an incurable and debilitating chronic progressive
neurodegenerative disorder which is the leading cause of dementia worldwide. AD is a …

The potential of stem cells in treatment of traumatic brain injury

NM Weston, D Sun - Current neurology and neuroscience reports, 2018 - Springer
Abstract Purpose of Review Traumatic brain injury (TBI) is a global public health concern,
with limited treatment options available. Despite improving survival rate after TBI, treatment …

[HTML][HTML] Early-onset network hyperexcitability in presymptomatic Alzheimer's disease transgenic mice is suppressed by passive immunization with anti-human APP/Aβ …

SF Kazim, SC Chuang, W Zhao, RKS Wong… - Frontiers in aging …, 2017 - frontiersin.org
Cortical and hippocampal network hyperexcitability appears to be an early event in
Alzheimer's disease (AD) pathogenesis, and may contribute to memory impairment. It …

Functional integration of adult-born hippocampal neurons after traumatic brain injury

LE Villasana, KN Kim, GL Westbrook, E Schnell - eneuro, 2015 - eneuro.org
Traumatic brain injury (TBI) increases hippocampal neurogenesis, which may contribute to
cognitive recovery after injury. However, it is unknown whether TBI-induced adult-born …

Endogenous neurogenic cell response in the mature mammalian brain following traumatic injury

D Sun - Experimental neurology, 2016 - Elsevier
In the mature mammalian brain, new neurons are generated throughout life in the
neurogenic regions of the subventricular zone (SVZ) and the dentate gyrus (DG) of the …

[HTML][HTML] Neuroepigenetic mechanisms of action of ultrashort peptides in Alzheimer's disease

A Ilina, V Khavinson, N Linkova… - International Journal of …, 2022 - mdpi.com
Epigenetic regulation of gene expression is necessary for maintaining higher-order
cognitive functions (learning and memory). The current understanding of the role of …

[HTML][HTML] A novel therapeutic approach to treat Alzheimer's disease by neurotrophic support during the period of synaptic compensation

N Baazaoui, K Iqbal - Journal of Alzheimer's Disease, 2018 - content.iospress.com
Abstract Alzheimer's disease (AD), at present, is considered an incurable disease and a
major dilemma with no drug to stop or slow down its progression. Drugs that are currently …

Acupuncture improved neurological recovery after traumatic brain injury by activating BDNF/TrkB pathway

X Li, C Chen, X Yang, J Wang, M Zhao… - Evidence‐Based …, 2017 - Wiley Online Library
How to promote neural repair following traumatic brain injury (TBI) has long been an
intractable problem. Although acupuncture has been demonstrated to facilitate the …

Strategies targeting endogenous neurogenic cell response to improve recovery following traumatic brain injury

K Patel, D Sun - Brain research, 2016 - Elsevier
Traumatic brain injury (TBI) affects over 1.7 million people in the United States alone and
poses many clinical challenges due to the variability of the injuries and complexity of …

Increases in microvascular perfusion and tissue oxygenation via vasodilatation after anodal transcranial direct current stimulation in the healthy and traumatized …

OA Bragina, DA Lara, EM Nemoto… - Oxygen Transport to …, 2018 - Springer
Traumatic brain injury (TBI), causing neurological deficit in 70% of survivors, still lacks a
clinically proven effective therapy. Transcranial direct current stimulation (tDCS) has …