Challenges and opportunities in C1-based biomanufacturing

W Qiao, S Xu, Z Liu, X Fu, H Zhao, S Shi - Bioresource Technology, 2022 - Elsevier
The intensifying impact of green-house gas (GHG) emission on environment and climate
change has attracted increasing attention, and biorefinery represents one of the most …

Recent progress in the engineering of C1-utilizing microbes

J Bae, S Jin, S Kang, BK Cho, MK Oh - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•C1 substrates are low-cost feedstocks supplied in abundance from waste
sources.•Microbial utilization of C1 substrates provides a sustainable conversion …

Physiological and stoichiometric characterization of ethanol-based chain elongation in the absence of short-chain carboxylic acids

MT Allaart, BB Fox, IHMS Nettersheim, M Pabst… - Scientific Reports, 2023 - nature.com
Hexanoate is a valuable chemical that can be produced by microorganisms that convert
short-chain-to medium-chain carboxylic acids through a process called chain elongation …

Molecular understanding of Eubacterium limosum chemostat methanol metabolism

JC Wood, RA Gonzalez-Garcia, D Daygon… - Sustainable Energy & …, 2023 - pubs.rsc.org
Methanol is a promising renewable energy carrier that can be used as a favourable
substrate for biotechnology, due to its high energy efficiency conversion and ease of …

Adaptive laboratory evolution of Clostridium autoethanogenum to metabolize CO2 and H2 enhances growth rates in chemostat and unravels proteome and …

J Heffernan, RA Garcia Gonzalez… - Microbial …, 2024 - Wiley Online Library
Gas fermentation of CO2 and H2 is an attractive means to sustainably produce fuels and
chemicals. Clostridium autoethanogenum is a model organism for industrial CO to ethanol …

Harnessing acetogenic bacteria for one-carbon valorization toward sustainable chemical production

J Bae, C Park, H Jung, S Jin, BK Cho - RSC Chemical Biology, 2024 - pubs.rsc.org
The pressing climate change issues have intensified the need for a rapid transition towards
a bio-based circular carbon economy. Harnessing acetogenic bacteria as biocatalysts to …

A novel experimental method to determine substrate uptake kinetics of gaseous substrates applied to the carbon monoxide‐fermenting Clostridium autoethanogenum

MT Allaart, C Korkontzelos, DZ Sousa… - Biotechnology and …, 2024 - Wiley Online Library
Syngas fermentation has gained momentum over the last decades. The cost‐efficient design
of industrial‐scale bioprocesses is highly dependent on quantitative microbial growth data …

Characterisation of acetogen formatotrophic potential using E. limosum

JC Wood, RA Gonzalez-Garcia, D Daygon, G Talbo… - bioRxiv, 2022 - biorxiv.org
Formate is a promising energy carrier that could be used to transport renewable electricity.
Some acetogenic bacteria, such as Eubacterium limosum, have the native ability to utilise …

Characterisation of acetogen formatotrophic potential using Eubacterium limosum

JC Wood, RA Gonzalez-Garcia, D Daygon… - Applied Microbiology …, 2023 - Springer
Formate is a promising energy carrier that could be used to transport renewable electricity.
Some acetogenic bacteria, such as Eubacterium limosum, have the native ability to utilise …

Progress in biomanufacturing of lipids and single cell protein from one-carbon compounds

Z Liang, LI Zhenshuai, FU Liping, LU Ming… - Synthetic Biology …, 2024 - synbioj.cip.com.cn
One-carbon compounds are liquid or gaseous substances that can be naturally occurring or
produced in industrial processes, offering the advantages of being abundant, cost-effective …