Stress and fear extinction

S Maren, A Holmes - Neuropsychopharmacology, 2016 - nature.com
Stress has a critical role in the development and expression of many psychiatric disorders,
and is a defining feature of posttraumatic stress disorder (PTSD). Stress also limits the …

[HTML][HTML] Prenatal stressors in rodents: Effects on behavior

M Weinstock - Neurobiology of stress, 2017 - Elsevier
The current review focuses on studies in rodents published since 2008 and explores
possible reasons for any differences they report in the effects of gestational stress on various …

Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood

AV Golubeva, S Crampton, L Desbonnet… - …, 2015 - Elsevier
Early-life adverse experiences, including prenatal stress (PNS), are associated with a higher
prevalence of neurodevelopmental, cardiovascular and metabolic disorders in affected …

Prenatal stress-induced increases in placental inflammation and offspring hyperactivity are male-specific and ameliorated by maternal antiinflammatory treatment

SL Bronson, TL Bale - Endocrinology, 2014 - academic.oup.com
Adverse experiences during gestation such as maternal stress and infection are known risk
factors for neurodevelopmental disorders, including schizophrenia, autism, and attention …

Mechanisms of shared vulnerability to post-traumatic stress disorder and substance use disorders

CE María-Ríos, JD Morrow - Frontiers in Behavioral Neuroscience, 2020 - frontiersin.org
Psychoactive substance use is a nearly universal human behavior, but a significant minority
of people who use addictive substances will go on to develop an addictive disorder …

Social interaction and social withdrawal in rodents as readouts for investigating the negative symptoms of schizophrenia

CA Wilson, JI Koenig - European Neuropsychopharmacology, 2014 - Elsevier
Negative symptoms (eg, asociality and anhedonia) are a distinct symptomatic domain that
has been found to significantly affect the quality of life in patients diagnosed with …

Pre-and neonatal exposure to lipopolysaccharide or the enteric metabolite, propionic acid, alters development and behavior in adolescent rats in a sexually dimorphic …

KA Foley, KP Ossenkopp, M Kavaliers, DF MacFabe - PLoS One, 2014 - journals.plos.org
Alterations in the composition of the gut microbiome and/or immune system function may
have a role in the development of autism spectrum disorders (ASD). The current study …

Sex differences in avoidance extinction after contextual fear conditioning: anxioescapic behavior in female rats

K Shanazz, R Dixon-Melvin, R Nalloor, R Thumar… - Neuroscience, 2022 - Elsevier
Fear memories are important for survival and are implicated in the etiology of fear disorders
such as Post Traumatic Stress Disorder (PTSD). Fear memories are well studied pre …

Mild prenatal stress causes emotional and brain structural modifications in rats of both sexes

C Soares-Cunha, B Coimbra, S Borges… - Frontiers in behavioral …, 2018 - frontiersin.org
Stress or high levels of glucocorticoids (GCs) during developmental periods is known to
induce persistent effects in the neuroendocrine circuits that control stress response, which …

Automated recording of home cage activity and temperature of individual rats housed in social groups: The Rodent Big Brother project

WS Redfern, K Tse, C Grant, A Keerie, DJ Simpson… - PloS one, 2017 - journals.plos.org
Measuring the activity and temperature of rats is commonly required in biomedical research.
Conventional approaches necessitate single housing, which affects their behavior and …