Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

H Cao, L Duan, Y Zhang, J Cao, K Zhang - Signal transduction and …, 2021 - nature.com
Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

Synthetic alternatives to Matrigel

EA Aisenbrey, WL Murphy - Nature Reviews Materials, 2020 - nature.com
Matrigel, a basement-membrane matrix extracted from Engelbreth–Holm–Swarm mouse
sarcomas, has been used for more than four decades for a myriad of cell-culture …

Reduced graphene oxide incorporated GelMA hydrogel promotes angiogenesis for wound healing applications

SR Rehman, R Augustine, AA Zahid… - International journal …, 2019 - Taylor & Francis
Purpose Non-healing or slow healing chronic wounds are among serious complications of
diabetes that eventually result in amputation of limbs and increased morbidities and …

Self-healing hydrogels: Preparation, mechanism and advancement in biomedical applications

A Devi VK, R Shyam, A Palaniappan, AK Jaiswal… - Polymers, 2021 - mdpi.com
Polymeric hydrogels are widely explored materials for biomedical applications. However,
they have inherent limitations like poor resistance to stimuli and low mechanical strength …

Hydrogel scaffolds to deliver cell therapies for wound healing

D Sivaraj, K Chen, A Chattopadhyay… - … in Bioengineering and …, 2021 - frontiersin.org
Cutaneous wounds are a growing global health burden as a result of an aging population
coupled with increasing incidence of diabetes, obesity, and cancer. Cell-based approaches …

Applications of hydrogel‐based delivery systems in wound care and treatment: An up‐to‐date review

G Divyashri, RV Badhe, B Sadanandan… - Polymers for …, 2022 - Wiley Online Library
Natural wound healing is a highly complex and regulated process. Disruption and barriers to
cellular and tissue repair processes contributes to impaired wound healing, including …

Advances in osteobiologic materials for bone substitutes

A Hasan, B Byambaa, M Morshed… - Journal of Tissue …, 2018 - Wiley Online Library
A significant challenge in the current orthopedics is the development of suitable
osteobiologic materials that can replace the conventional allografts, autografts, and …

[HTML][HTML] Stem cell-based approaches in cardiac tissue engineering: controlling the microenvironment for autologous cells

R Augustine, P Dan, A Hasan, IM Khalaf… - Biomedicine & …, 2021 - Elsevier
Cardiovascular disease is one of the leading causes of mortality worldwide. Cardiac tissue
engineering strategies focusing on biomaterial scaffolds incorporating cells and growth …

Recent advances in the design of injectable hydrogels for stem cell-based therapy

K Liang, KH Bae, M Kurisawa - Journal of Materials Chemistry B, 2019 - pubs.rsc.org
Stem cell therapy holds promise for the treatment of many diseases but the efficacy is limited
by the unfavorable environments in the impaired tissues. The use of hydrogel scaffolds has …

Nitric oxide releasing chitosan-poly (vinyl alcohol) hydrogel promotes angiogenesis in chick embryo model

AA Zahid, R Ahmed, SR ur Rehman… - International journal of …, 2019 - Elsevier
The lack of angiogenic activity is one of the serious complications of chronic wounds
associated with delayed wound closure, chronic ulceration, and subsequent limb …