Diagnosis of multiple sclerosis: progress and challenges

WJ Brownlee, TA Hardy, F Fazekas, DH Miller - The Lancet, 2017 - thelancet.com
The diagnosis of multiple sclerosis is based on neurological symptoms and signs, alongside
evidence of dissemination of CNS lesions in space and time. MRI is often sufficient to …

Atypical inflammatory demyelinating syndromes of the CNS

TA Hardy, SW Reddel, MH Barnett, J Palace… - The Lancet …, 2016 - thelancet.com
Atypical inflammatory demyelinating syndromes are rare disorders that differ from multiple
sclerosis owing to unusual clinical or MRI findings or poor response to treatments used for …

[HTML][HTML] Uncovering convolutional neural network decisions for diagnosing multiple sclerosis on conventional MRI using layer-wise relevance propagation

F Eitel, E Soehler, J Bellmann-Strobl, AU Brandt… - NeuroImage: Clinical, 2019 - Elsevier
Abstract Machine learning-based imaging diagnostics has recently reached or even
surpassed the level of clinical experts in several clinical domains. However, classification …

Neuroinflammation and its association with cognition, neuronal markers and peripheral inflammation after chemotherapy for breast cancer

G Schroyen, J Blommaert, D van Weehaeghe, C Sleurs… - Cancers, 2021 - mdpi.com
Simple Summary Up to 70% of chemotherapy-treated patients experience problems with
memory and concentration, potentially caused by direct and indirect neurotoxicity, such as …

A review on brain structures segmentation in magnetic resonance imaging

S González-Villà, A Oliver, S Valverde, L Wang… - Artificial intelligence in …, 2016 - Elsevier
Background and objectives Automatic brain structures segmentation in magnetic resonance
images has been widely investigated in recent years with the goal of helping diagnosis and …

Susac syndrome: neurological update (clinical features, long-term observational follow-up and management of sixteen patients)

S Bose, A Papathanasiou, S Karkhanis, JP Appleton… - Journal of …, 2023 - Springer
Susac syndrome is a likely autoimmune microangiopathy affecting the brain, retina and
inner ear. Due to the rarity of this condition, diagnosis and treatment can be challenging …

Diagnosis, differential diagnosis and misdiagnosis of Susac syndrome

JD Triplett, J Qiu, B O'Brien, S Gopinath… - European journal of …, 2022 - Wiley Online Library
Background and purpose Susac syndrome (SuS) is an inflammatory condition of the brain,
eye and ear. Diagnosis can be challenging, and misdiagnosis is common. Methods This is a …

Cytotoxic lesions of the corpus callosum: a systematic review

S Moors, D Nakhostin, D Ilchenko, Z Kulcsar… - European …, 2024 - Springer
Objectives Cytotoxic lesions of the corpus callosum (CLOCC) are a common magnetic
resonance imaging (MRI) finding associated with various systemic diseases including …

Pseudotumoral demyelinating lesions: diagnostic approach and long-term outcome

TA Hardy - Current opinion in neurology, 2019 - journals.lww.com
Not all patients with pseudotumoral lesions require a brain biopsy but close follow-up of
biopsied and nonbiopsied lesions is indicated once a diagnosis is established. Testing for …

Structural properties of the human corpus callosum: Multimodal assessment and sex differences

L Björnholm, J Nikkinen, V Kiviniemi, T Nordström… - Neuroimage, 2017 - Elsevier
A number of structural properties of white matter can be assessed in vivo using multimodal
magnetic resonance imaging (MRI). We measured profiles of R1 and R2 relaxation rates …