In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

Currently, a small number of diseases, particularly cardiovascular (CVDs), oncologic (ODs),
neurodegenerative (NDDs), chronic respiratory diseases, as well as diabetes, form a severe …

The methodology for EPOS2012 has been the same as for the other two productions.
Leaders in the field were invited to critically appraise the literature and write a report on a …

During the past decade a plethora of studies have unravelled the multiple roles of nitric
oxide (NO) in airway physiology and pathophysiology. In the respiratory tract, NO is …

There has recently been an explosion of interest in the analysis of breath constituents as a
way of monitoring inflammation and oxidative stress in the lungs. Here we review the use of …

Asthma is a complex chronic inflammatory disease of the airways that involves the activation
of many inflammatory and structural cells, all of which release inflammatory mediators that …

Inhaled corticosteroids have revolutionized the treatment of asthma and have now become
the mainstay of therapy for patients with chronic disease (1). In a supplement to this journal …

Nitric oxide is endogenously released in the airways by nitric oxide synthase. Functionally,
two isoforms of this enzyme exist: constitutive and inducible. The former seems to protect …

1. Background Nitric oxide (NO) gas, which is produced by various cells within the
respiratory tract, is detectable in the exhaled air [1, 2], and plays an important role in the …

Cigarette smoking is associated with an increased risk of respiratory tract infections, chronic
airway disease, and cardiovascular diseases, all of which may be modulated by …