Extrahepatic morbidity and mortality of chronic hepatitis C

F Negro, D Forton, A Craxì, MS Sulkowski, JJ Feld… - Gastroenterology, 2015 - Elsevier
Chronic hepatitis C virus (HCV) infection is associated with several extrahepatic
manifestations. Patients with HCV may develop mixed cryoglobulinemia and its sequelae …

Mechanisms of hepatic fibrogenesis

SL Friedman - Gastroenterology, 2008 - Elsevier
Substantial improvements in the treatment of chronic liver disease have accelerated interest
in uncovering the mechanisms underlying hepatic fibrosis and its resolution. Activation of …

[PDF][PDF] Hepatitis C guidance 2019 update: American Association for the Study of Liver Diseases–Infectious Diseases Society of America recommendations for testing …

MG Ghany, TR Morgan… - …, 2020 - Wiley Online Library
HCV infection, risk-based screening failed to identify the majority of individuals with HCV
infection due to both clinician and patient barriers.(9-12) Analysis of the 2003-2010 National …

[HTML][HTML] A position statement on NAFLD/NASH based on the EASL 2009 special conference

V Ratziu, S Bellentani, H Cortez-Pinto… - Journal of …, 2010 - journal-of-hepatology.eu
Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are
increasingly relevant public health issues owing to their close association with the …

Diabetes mellitus in patients with cirrhosis: clinical implications and management

L Elkrief, PE Rautou, S Sarin, D Valla… - Liver …, 2016 - Wiley Online Library
Disorders of glucose metabolism, namely glucose intolerance and diabetes, are frequent in
patients with chronic liver diseases. In patients with cirrhosis, diabetes can be either a …

[HTML][HTML] Histopathology of nonalcoholic fatty liver disease

EM Brunt, DG Tiniakos - World journal of gastroenterology: WJG, 2010 - ncbi.nlm.nih.gov
Histological analysis of liver biopsies remains a standard against which other methods of
assessment for the presence and amount of hepatic injury due to nonalcoholic fatty liver …

[HTML][HTML] Liver cirrhosis and diabetes: risk factors, pathophysiology, clinical implications and management

D Garcia-Compean, JO Jaquez-Quintana… - World journal of …, 2009 - ncbi.nlm.nih.gov
About 30% of patients with cirrhosis have diabetes mellitus (DM). Nowadays, it is a matter for
debate whether type 2 DM in the absence of obesity and hypertriglyceridemia may be a risk …

[PDF][PDF] Low vitamin D serum level is related to severe fibrosis and low responsiveness to interferon‐based therapy in genotype 1 chronic hepatitis C

S Petta, C Cammà, C Scazzone, C Tripodo… - …, 2010 - Wiley Online Library
Hydroxyvitamin D (25 [OH] D) can potentially interfere with inflammatory response and
fibrogenesis. Its role in disease progression in chronic hepatitis C (CHC) and its relation with …

Systematic review: chronic viral hepatitis and metabolic derangement

CC Wang, PN Cheng, JH Kao - Alimentary pharmacology & …, 2020 - Wiley Online Library
Background The liver has a critical role in the metabolism of glucose and lipids. Chronic
hepatitis B virus (HBV) or hepatitis C virus (HCV) infection leads to a spectrum of liver …

[PDF][PDF] Antiviral treatment for hepatitis C virus infection is associated with improved renal and cardiovascular outcomes in diabetic patients

YC Hsu, JT Lin, HJ Ho, YH Kao, YT Huang… - …, 2014 - Wiley Online Library
Hepatitis C virus (HCV) infection is causally associated with insulin resistance and diabetes
mellitus. This population‐based cohort study aimed to investigate whether antiviral therapy …