Diabetes management in chronic kidney disease: a consensus report by the American Diabetes Association (ADA) and Kidney Disease: Improving Global Outcomes …

IH de Boer, K Khunti, T Sadusky, KR Tuttle… - Diabetes …, 2022 - Am Diabetes Assoc
People with diabetes and chronic kidney disease (CKD) are at high risk for kidney failure,
atherosclerotic cardiovascular disease, heart failure, and premature mortality. Recent …

New horizons of macrophage immunomodulation in the healing of diabetic foot ulcers

CW Lin, CM Hung, WJ Chen, JC Chen, WY Huang… - Pharmaceutics, 2022 - mdpi.com
Diabetic foot ulcers (DFUs) are one of the most costly and troublesome complications of
diabetes mellitus. The wound chronicity of DFUs remains the main challenge in the current …

Frailty and risk of microvascular complications in patients with type 2 diabetes: a population-based cohort study

Y Wu, T Xiong, X Tan, L Chen - BMC medicine, 2022 - Springer
Background Cross-sectional studies found that frailty was associated with prevalent diabetic
microvascular complications (DMC). Longitudinal evidence in this regard is inconclusive …

Astaxanthin protects retinal photoreceptor cells against high glucose-induced oxidative stress by induction of antioxidant enzymes via the PI3K/Akt/Nrf2 pathway

TT Lai, CM Yang, CH Yang - Antioxidants, 2020 - mdpi.com
Diabetic retinopathy (DR) is a major microvascular complication that can lead to severe
visual impairment in patients with diabetes. The elevated oxidative stress and increased …

Chronic kidney outcomes associated with GLP-1 receptor agonists versus long-acting insulins among type 2 diabetes patients requiring intensive glycemic control: a …

ZY Peng, CT Yang, WH Lin, WY Yao, HT Ou… - Cardiovascular …, 2023 - Springer
Background Effectiveness of glucagon-like peptide-1 receptor agonists (GLP-1RAs) versus
long-acting insulins (LAIs) on preventing progressive chronic kidney outcomes is uncertain …

Medical costs associated with diabetes complications in Medicare beneficiaries aged 65 years or older with type 2 diabetes

Y Wang, P Zhang, H Shao, LJ Andes… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE To estimate medical costs associated with 17 major diabetes-related
complications and treatment procedures among Medicare beneficiaries aged≥ 65 years …

Association between triglyceride-glucose index and risk of end-stage renal disease in patients with type 2 diabetes mellitus and chronic kidney disease

YM Gao, WJ Chen, ZL Deng, Z Shang… - Frontiers in …, 2023 - frontiersin.org
Aims It has been suggested that the triglyceride-glucose (TyG) index is a novel and reliable
surrogate marker of insulin resistance (IR). However, its relationship with the risk of end …

Progression and regression of nerve fibre pathology and dysfunction early in diabetes over 5 years

D Ziegler, GJ Bönhof, A Strom, K Straßburger… - Brain, 2021 - academic.oup.com
It has traditionally been suggested that the early development of diabetic sensorimotor
polyneuropathy (DSPN) is characterized by predominant and progressive injury to small …

Investigating the causal association of generalized and abdominal obesity with microvascular complications in patients with type 2 diabetes: A community‐based …

J Chen, YT Li, Z Niu, Z He, YJ Xie… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aim The paradoxical protective association between overweight/obesity and diabetic
microvascular complications (DMC), a phenomenon well‐known as the obesity paradox …

Derivation and validation of a prediction model of end-stage renal disease in patients with type 2 diabetes based on a systematic review and meta-analysis

Q Ren, D Chen, X Liu, R Yang, L Yuan… - Frontiers in …, 2022 - frontiersin.org
Objectives To develop and validate a model for predicting the risk of end-stage renal
disease (ESRD) in patients with type 2 diabetes. Methods The derivation cohort was from a …