Identification of intrinsic brain activity differences and similarities between major depression
(MDD) and bipolar disorder (BD) is necessary. However, results have not yet yielded …

In patients with major depressive disorder or bipolar disorder, abnormalities in excitatory
and/or inhibitory neurotransmission and neuronal plasticity may lead to aberrant functional …

Background The observation that mismatch negativity (MMN) is consistently impaired in
schizophrenia has generated considerable interest in the use of this biomarker as an index …

This brief review article makes the argument that glutamate is deserving of its newfound
attention within the neuroscience literature and that many directions of important research …

Lithium has been used for the treatment of bipolar disorder (BD) for the last sixty or more
years, and recent studies with more reliable designs and updated guidelines have …

Glutamate (Glu) and gamma-aminobutyric acid (GABA) are implicated in the
pathophysiology of major depressive disorder (MDD). GABA levels or GABAergic …

From a neurobiological perspective there is no such thing as bipolar disorder. Rather, it is
almost certainly the case that many somewhat similar, but subtly different, pathological …

Excessive glutamate release has been linked to stress and many neurodegenerative
diseases. Evidence indicates abnormalities of glutamatergic neurotransmission or …

The integration of multiple imaging modalities is becoming an increasingly well used
research strategy for studying the human brain. The neurotransmitters glutamate and GABA …

Bipolar disorder is a severe and enduring psychiatric condition which in many cases starts
during early adulthood and follows a relapsing and remitting course throughout life. In many …