Gemtuzumab ozogamicin and novel antibody-drug conjugates in clinical trials for acute myeloid leukemia

B Yu, D Liu - Biomarker research, 2019 - Springer
Targeted agents are increasingly used for the therapy of acute myeloid leukemia (AML).
Gemtuzumab ozogamicin (GO) is the first antibody-drug conjugate (ADC) approved for …

Cancer biomarkers for targeted therapy

D Liu - Biomarker research, 2019 - Springer
Tumor-associated antigens (TAA) or cancer biomarkers are major targets for cancer
therapies. Antibody-based agents targeting the cancer biomarkers include monoclonal …

Clinical benefits and safety of gemtuzumab ozogamicin in treating acute myeloid leukemia in various subgroups: an updated systematic review, meta-analysis, and …

Q Xu, S He, L Yu - Frontiers in Immunology, 2021 - frontiersin.org
Background Previous trials demonstrated evidence involving the total effects of gemtuzumab
ozogamicin (GO), an anti-CD33 humanized antibody, on treating acute myeloid leukemia …

[HTML][HTML] Anticancer agent effect and polychemotherapy regimens for malignant tumor treatment-a review

NA Chrysanthakopoulos, E Vryzaki - Galician medical journal, 2022 - ifnmujournal.com
Cancer is a leading cause of millions of deaths worldwide and, despite the improvements in
molecular biology, issues concerning how to advance cancer treatment are still relevant …

A method for assessing robustness of the results of a star-shaped network meta-analysis under the unidentifiable consistency assumption

JH Yoon, S Dias, S Hahn - BMC Medical Research Methodology, 2021 - Springer
Background In a star-shaped network, pairwise comparisons link treatments with a reference
treatment (often placebo or standard care), but not with each other. Thus, comparisons …