Metal-catalysed C–Het (F, O, S, N) and C–C bond arylation
B Zhao, T Rogge, L Ackermann, Z Shi - Chemical Society Reviews, 2021 - pubs.rsc.org
The formation of C–aryl bonds has been the focus of intensive research over the last
decades for the construction of complex molecules from simple, readily available feedstocks …
decades for the construction of complex molecules from simple, readily available feedstocks …
Recent advances in acyl Suzuki cross-coupling
J Buchspies, M Szostak - Catalysts, 2019 - mdpi.com
Acyl Suzuki cross-coupling involves the coupling of an organoboron reagent with an acyl
electrophile (acyl halide, anhydride, ester, amide). This review provides a timely overview of …
electrophile (acyl halide, anhydride, ester, amide). This review provides a timely overview of …
Nickel‐Catalyzed Synthesis of Dialkyl Ketones from the Coupling of N‐Alkyl Pyridinium Salts with Activated Carboxylic Acids
J Wang, ME Hoerrner, MP Watson… - Angewandte …, 2020 - Wiley Online Library
While ketones are among the most versatile functional groups, their synthesis remains
reliant upon reactive and low‐abundance starting materials. In contrast, amide formation is …
reliant upon reactive and low‐abundance starting materials. In contrast, amide formation is …
Mechanism and scope of nickel-catalyzed decarbonylative borylation of carboxylic acid fluorides
CA Malapit, JR Bour, SR Laursen… - Journal of the American …, 2019 - ACS Publications
This Article describes the development of a base-free, nickel-catalyzed decarbonylative
coupling of carboxylic acid fluorides with diboron reagents to selectively afford aryl boronate …
coupling of carboxylic acid fluorides with diboron reagents to selectively afford aryl boronate …
Palladium‐Catalyzed Decarbonylative Trifluoromethylation of Acid Fluorides
ST Keaveney, F Schoenebeck - Angewandte Chemie, 2018 - Wiley Online Library
While acid fluorides can readily be made from widely available or biomass‐feedstock‐
derived carboxylic acids, their use as functional groups in metal‐catalyzed cross‐coupling …
derived carboxylic acids, their use as functional groups in metal‐catalyzed cross‐coupling …
Carbamoyl fluoride-enabled enantioselective Ni-catalyzed carbocarbamoylation of unactivated alkenes
Y Li, FP Zhang, RH Wang, SL Qi… - Journal of the American …, 2020 - ACS Publications
Carbamoyl Fluoride-Enabled Enantioselective Ni-Catalyzed Carbocarbamoylation of
Unactivated Alkenes | Journal of the American Chemical Society ACS ACS Publications …
Unactivated Alkenes | Journal of the American Chemical Society ACS ACS Publications …
Synthesis of N-CF3 Alkynamides and Derivatives Enabled by Ni-Catalyzed Alkynylation of N-CF3 Carbamoyl Fluorides
CDT Nielsen, FG Zivkovic… - Journal of the American …, 2021 - ACS Publications
The expansion of chemical space associated with ubiquitous motifs is key to unleash new
properties and functions. In this context, alkynamides, prevalent in numerous drugs and …
properties and functions. In this context, alkynamides, prevalent in numerous drugs and …
Palladium-catalyzed reductive conversion of acyl fluorides via ligand-controlled decarbonylation
Y Ogiwara, Y Sakurai, H Hattori, N Sakai - Organic letters, 2018 - ACS Publications
Ligand-controlled non-decarbonylative and decarbonylative conversions of acyl fluorides
were developed using a Pd (OAc) 2/Et3SiH combination. When tricyclohexylphosphine …
were developed using a Pd (OAc) 2/Et3SiH combination. When tricyclohexylphosphine …
Direct access to acyl fluorides from carboxylic acids using a phosphine/fluoride deoxyfluorination reagent system
A fast and simple method for deoxyfluorination of carboxylic acids is presented. The protocol
employs commodity chemicals (PPh3, NBS, fluoride), affording products in excellent yields …
employs commodity chemicals (PPh3, NBS, fluoride), affording products in excellent yields …
Acyl fluorides from carboxylic acids, aldehydes, or alcohols under oxidative fluorination
We describe a novel reagent system to obtain acyl fluorides directly from three different
functional group precursors: carboxylic acids, aldehydes, or alcohols. The transformation is …
functional group precursors: carboxylic acids, aldehydes, or alcohols. The transformation is …