Background Over the past 2 decades, the use of intravenous ketamine infusions as a
treatment for chronic pain has increased dramatically, with wide variation in patient …

Definition and taxonomy This review deals with neuropathic pain of traumatic origin affecting
the trigeminal nerve, ie painful post-traumatic trigeminal neuropathy (PTTN) …

Objective: To investigate the efficacy of N-methyl-D-aspartate receptor (NMDAR) antagonists
for neuropathic pain (NeuP) and review literature to determine if specific pharmacologic …

This health technology assessment evaluated the efficacy of pharmacological treatment in
patients with oro‐facial pain. Randomised controlled trials were included if they reported …

A still commonly held view in the literature and clinical practice is that bruxism causes pain
because of overloading of the musculoskeletal tissue and craniofacial pain, on the other …

Oral analgesics are commonly prescribed for the treatment of acute and chronic pain, but
these agents often produce adverse systemic effects, which sometimes are severe. Topical …

Chronic oro‐facial pain conditions such as persistent idiopathic facial pain (PIFP), atypical
odontalgia (AO) and burning mouth syndrome (BMS), usually grouped together under the …

Atypical odontalgia (AO) is a chronic form of dental pain without signs of pathology. Several
hypotheses have been put forward regarding the pathophysiology. AO has been proposed …

Intraoral somatosensory sensitivity in patients with atypical odontalgia (AO) has not been
investigated systematically according to the most recent guidelines. The aims of this study …

Importance of the field: Worldwide the number of patients affected by chronic pain is growing
and conventional treatment is often insufficient. Recently the importance of the N-methyl-d …