[HTML][HTML] Tubular cell glucose metabolism shift during acute and chronic injuries

A Faivre, T Verissimo, H Auwerx, D Legouis… - Frontiers in …, 2021 - frontiersin.org
Acute and chronic kidney disease are responsible for large healthcare costs worldwide.
During injury, kidney metabolism undergoes profound modifications in order to adapt to …

Gluconeogenesis in the kidney: in health and in chronic kidney disease

D Dalga, T Verissimo, S De Seigneux - Clinical Kidney Journal, 2023 - academic.oup.com
Chronic kidney disease (CKD) is a global health issue with increasing prevalence. Despite
large improvements in current therapies, slowing CKD progression remains a challenge. A …

[HTML][HTML] Mortality and associated risk factors in patients with blood culture positive sepsis and acute kidney injury requiring continuous renal replacement therapy—A …

MJ Järvisalo, T Hellman, P Uusalo - PLoS One, 2021 - journals.plos.org
Objectives Septic acute kidney injury (AKI) requiring continuous renal replacement therapy
(CRRT) carries a mortality risk nearing 50%. Risk factors associated with mortality in AKI …

Natural history, spectrum and outcome of stage 3 AKI in patients with acute‐on‐chronic liver failure

R Maiwall, A Rastogi, SSR Pasupuleti… - Liver …, 2022 - Wiley Online Library
Abstract Background and Aim There is limited data on natural course and interventions in
stage‐3 acute kidney injury (AKI‐3) in patients with acute‐on‐chronic liver failure (ACLF) …

Serum lactate level accurately predicts mortality in critically ill patients with cirrhosis with acute kidney injury

DQ Sun, CF Zheng, FB Lu, S Van Poucke… - European Journal of …, 2018 - journals.lww.com
Results Compared with patients in the survival group, nonsurvivors had higher serum lactate
levels. Mortality rate increased progressively as the serum lactate level increased (Q1 …

Development of vancomycin dose individualization strategy by bayesian prediction in patients receiving continuous renal replacement therapy

K Oda, H Jono, H Kamohara, K Nishi, N Tanoue… - Pharmaceutical …, 2020 - Springer
Purpose Vancomycin (VCM) concentration is often out of therapeutic range (10–20 μg/ml) in
patients receiving continuous renal replacement therapy (CRRT). The purposes of this study …

Standard renal replacement therapy combined with hemoadsorption in the treatment of critically ill septic patients

M Popescu, S Dima, C David, A Tudor… - Therapeutic …, 2021 - Wiley Online Library
The aim of the study was to assess clinical and paraclinical effects of hemoadsorption on
organ dysfunction, severity scores, and 28‐day survival in septic patients. Fifty‐five septic …

[HTML][HTML] Predialysis serum lactate levels could predict dialysis withdrawal in Type 1 cardiorenal syndrome patients

HC Pan, TM Huang, CY Sun, NK Chou, CH Tsao… - …, 2022 - thelancet.com
Background Renal replacement therapy (RRT) is an effective rescue therapy for Type 1
cardiorenal syndrome (CRS). Previous studies have demonstrated that type 1 CRS patients …

[HTML][HTML] The association between continuous renal replacement therapy as treatment for sepsis-associated acute kidney injury and trend of lactate trajectory as risk …

Z Wang, L Zhang, F Xu, D Han, J Lyu - BMC Emergency Medicine, 2022 - Springer
Background Sepsis has high incidence and fatality rates in intensive care units, often
leading to renal failure. The effectiveness of continuous renal replacement therapy (CRRT) …

[HTML][HTML] Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury

SG Kim, J Lee, D Yun, MW Kang, YC Kim, DK Kim… - BMC nephrology, 2023 - Springer
Background Hyperlactatemia occurs frequently in critically ill patients, and this pathologic
condition leads to worse outcomes in several disease subsets. Herein, we addressed …