[HTML][HTML] Tubular cell glucose metabolism shift during acute and chronic injuries
Acute and chronic kidney disease are responsible for large healthcare costs worldwide.
During injury, kidney metabolism undergoes profound modifications in order to adapt to …
During injury, kidney metabolism undergoes profound modifications in order to adapt to …
Gluconeogenesis in the kidney: in health and in chronic kidney disease
D Dalga, T Verissimo, S De Seigneux - Clinical Kidney Journal, 2023 - academic.oup.com
Chronic kidney disease (CKD) is a global health issue with increasing prevalence. Despite
large improvements in current therapies, slowing CKD progression remains a challenge. A …
large improvements in current therapies, slowing CKD progression remains a challenge. A …
[HTML][HTML] Mortality and associated risk factors in patients with blood culture positive sepsis and acute kidney injury requiring continuous renal replacement therapy—A …
MJ Järvisalo, T Hellman, P Uusalo - PLoS One, 2021 - journals.plos.org
Objectives Septic acute kidney injury (AKI) requiring continuous renal replacement therapy
(CRRT) carries a mortality risk nearing 50%. Risk factors associated with mortality in AKI …
(CRRT) carries a mortality risk nearing 50%. Risk factors associated with mortality in AKI …
Natural history, spectrum and outcome of stage 3 AKI in patients with acute‐on‐chronic liver failure
R Maiwall, A Rastogi, SSR Pasupuleti… - Liver …, 2022 - Wiley Online Library
Abstract Background and Aim There is limited data on natural course and interventions in
stage‐3 acute kidney injury (AKI‐3) in patients with acute‐on‐chronic liver failure (ACLF) …
stage‐3 acute kidney injury (AKI‐3) in patients with acute‐on‐chronic liver failure (ACLF) …
Serum lactate level accurately predicts mortality in critically ill patients with cirrhosis with acute kidney injury
DQ Sun, CF Zheng, FB Lu, S Van Poucke… - European Journal of …, 2018 - journals.lww.com
Results Compared with patients in the survival group, nonsurvivors had higher serum lactate
levels. Mortality rate increased progressively as the serum lactate level increased (Q1 …
levels. Mortality rate increased progressively as the serum lactate level increased (Q1 …
Development of vancomycin dose individualization strategy by bayesian prediction in patients receiving continuous renal replacement therapy
K Oda, H Jono, H Kamohara, K Nishi, N Tanoue… - Pharmaceutical …, 2020 - Springer
Purpose Vancomycin (VCM) concentration is often out of therapeutic range (10–20 μg/ml) in
patients receiving continuous renal replacement therapy (CRRT). The purposes of this study …
patients receiving continuous renal replacement therapy (CRRT). The purposes of this study …
Standard renal replacement therapy combined with hemoadsorption in the treatment of critically ill septic patients
M Popescu, S Dima, C David, A Tudor… - Therapeutic …, 2021 - Wiley Online Library
The aim of the study was to assess clinical and paraclinical effects of hemoadsorption on
organ dysfunction, severity scores, and 28‐day survival in septic patients. Fifty‐five septic …
organ dysfunction, severity scores, and 28‐day survival in septic patients. Fifty‐five septic …
[HTML][HTML] Predialysis serum lactate levels could predict dialysis withdrawal in Type 1 cardiorenal syndrome patients
HC Pan, TM Huang, CY Sun, NK Chou, CH Tsao… - …, 2022 - thelancet.com
Background Renal replacement therapy (RRT) is an effective rescue therapy for Type 1
cardiorenal syndrome (CRS). Previous studies have demonstrated that type 1 CRS patients …
cardiorenal syndrome (CRS). Previous studies have demonstrated that type 1 CRS patients …
[HTML][HTML] The association between continuous renal replacement therapy as treatment for sepsis-associated acute kidney injury and trend of lactate trajectory as risk …
Z Wang, L Zhang, F Xu, D Han, J Lyu - BMC Emergency Medicine, 2022 - Springer
Background Sepsis has high incidence and fatality rates in intensive care units, often
leading to renal failure. The effectiveness of continuous renal replacement therapy (CRRT) …
leading to renal failure. The effectiveness of continuous renal replacement therapy (CRRT) …
[HTML][HTML] Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury
Background Hyperlactatemia occurs frequently in critically ill patients, and this pathologic
condition leads to worse outcomes in several disease subsets. Herein, we addressed …
condition leads to worse outcomes in several disease subsets. Herein, we addressed …