More than one third of ovarian cancer patients present with ascites at diagnosis, and almost
all have ascites at recurrence. The presence of ascites correlates with the peritoneal spread …

Simple Summary Accumulation of excess fluid in the abdomen typically indicates abnormal
function or disease, such as cancer, in the underlying tissues. This accumulation of fluid, or …

Objective: In tumor patients, IL-6 appears to be one component of a consistent cancer-
associated cytokine network resulting in both a systemic immune stimulation and a …

Fatigue is one of the most prevalent and distressing symptoms of cancer, and is a common
side-effect of many of the treatments available for the management of malignant disease. We …

Inflammation plays a role in the initiation and development of many types of cancers,
including epithelial ovarian cancer (EOC) and high grade serous ovarian cancer (HGSC), a …

Metastasis from epithelial ovarian cancer can occur via the transcoelomic,
haematogeneous, or lymphatic route. Of these, transcoelomic metastasis is the most …

Abstract Interleukin‐6 (IL‐6) is a multifunctional cytokine produced by macrophages, T cells,
B cells, endothelial cells and tumour cells. Interleukin‐6 is able to promote tumour growth by …

Abstract Interleukin (IL)-6, a pleiotropic cytokine with varied systemic functions, plays a major
role in inflammatory processes. It modulates the transcription of several liver-specific genes …

Purpose Early detection of ovarian cancer has great promise to improve clinical outcome.
Patients and Methods Ninety-six serum biomarkers were analyzed in sera from healthy …

Angiogenesis, a key rate-limiting step in the growth and dissemination of malignant tumors,
is regulated by the balance between positive and negative effectors. Recent studies indicate …