The transition from mitosis to interphase, referred to as mitotic exit, is a critical mitotic
process which involves activation and inactivation of multiple mitotic kinases and …

A complex network precisely regulates the cell cycle through the G1, S, G2, and M phases
and is the basis for cell division under physiological and pathological conditions. On the one …

Epithelial ovarian cancer (EOC), a common tumor of the female reproductive system, ranks
first in fatalities among gynecological malignancies. Most patients find tumors at late stage …

Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype, lacking
effective therapy. Many TNBCs show remarkable response to carboplatin-based …

Epithelial cancer of the ovary exhibits the highest mortality rate of all gynecological
malignancies in women today, since the disease is often diagnosed in advanced stages …

Fibrosis is a common pathological phenomenon in progressive kidney disease leading to
eventual loss of kidney function. Previous studies demonstrated that CDC20 plays a role in …

The anaphase‐promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that helps
control chromosome separation and exit from mitosis in many different kinds of organisms …

Background Tumor immune microenvironment (TIM) plays a critical role in tumorigenesis
and progression. Recently, therapies based on modulating TIM have made great …

Ovarian cancer, a major gynecological malignancy, often remains undetected until
advanced stages, necessitating more effective early screening methods. Existing biomarker …

Ovarian cancer (OC) cells frequently metastasize to the omentum, and adipocytes play a
significant role in ovarian tumor progression. Therapeutic interventions targeting aberrant …