[HTML][HTML] A comprehensive and biophysically detailed computational model of the whole human heart electromechanics

M Fedele, R Piersanti, F Regazzoni, M Salvador… - Computer Methods in …, 2023 - Elsevier
While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …

Modeling cardiac muscle fibers in ventricular and atrial electrophysiology simulations

R Piersanti, PC Africa, M Fedele, C Vergara… - Computer Methods in …, 2021 - Elsevier
Since myocardial fibers drive the electric signal propagation throughout the myocardium,
accurately modeling their arrangement is essential for simulating heart electrophysiology …

Personalized cardiac computational models: from clinical data to simulation of infarct-related ventricular tachycardia

A Lopez-Perez, R Sebastian, M Izquierdo… - Frontiers in …, 2019 - frontiersin.org
In the chronic stage of myocardial infarction, a significant number of patients develop life-
threatening ventricular tachycardias (VT) due to the arrhythmogenic nature of the remodeled …

Hemodynamics of the heart's left atrium based on a variational multiscale-LES numerical method

A Zingaro, F Menghini, A Quarteroni - European Journal of Mechanics-B …, 2021 - Elsevier
In this paper, we investigate the haemodynamics of a left atrium (LA) by proposing a
computational model suitable to provide physically meaningful fluid dynamics indications …

Constructing a human atrial fibre atlas

CH Roney, R Bendikas, F Pashakhanloo… - Annals of biomedical …, 2021 - Springer
Atrial anisotropy affects electrical propagation patterns, anchor locations of atrial reentrant
drivers, and atrial mechanics. However, patient-specific atrial fibre fields and anisotropy …

An expert review of the inverse problem in electrocardiographic imaging for the non-invasive identification of atrial fibrillation drivers

Z Yadan, L Jian, W Jian, L Yifu, L Haiying - Computer Methods and …, 2023 - Elsevier
Abstract Background and Objective Electrocardiographic imaging (ECGI) has emerged as a
non-invasive approach to identify atrial fibrillation (AF) driver sources. This paper aims to …

lifex-fiber: an open tool for myofibers generation in cardiac computational models

PC Africa, R Piersanti, M Fedele, L Dede'… - BMC …, 2023 - Springer
Background Modeling the whole cardiac function involves the solution of several complex
multi-physics and multi-scale models that are highly computationally demanding, which call …

Analysis of a coupled fluid‐structure interaction model of the left atrium and mitral valve

L Feng, H Gao, B Griffith, S Niederer… - International journal for …, 2019 - Wiley Online Library
We present a coupled left atrium‐mitral valve model based on computed tomography scans
with fibre‐reinforced hyperelastic materials. Fluid‐structure interaction is realised by using …

A publicly available virtual cohort of four-chamber heart meshes for cardiac electro-mechanics simulations

M Strocchi, CM Augustin, MAF Gsell, E Karabelas… - PloS one, 2020 - journals.plos.org
Computational models of the heart are increasingly being used in the development of
devices, patient diagnosis and therapy guidance. While software techniques have been …

ECG-based data-driven solutions for diagnosis and prognosis of cardiovascular diseases: A systematic review

PA Moreno-Sánchez, G García-Isla, VDA Corino… - Computers in Biology …, 2024 - Elsevier
Cardiovascular diseases (CVD) are a leading cause of death globally, and result in
significant morbidity and reduced quality of life. The electrocardiogram (ECG) plays a crucial …