A review on analytical strategies for the assessment of recently approved direct acting antiviral drugs
Human beings are in dire need of developing an efficient treatment against fierce viruses
like hepatitis C virus (HCV) and Coronavirus (COVID-19). These viruses have already …
like hepatitis C virus (HCV) and Coronavirus (COVID-19). These viruses have already …
In-vitro and in-vivo evaluation of velpatasvir-loaded mesoporous silica scaffolds. A prospective carrier for drug bioavailability enhancement
The limited aqueous solubility of many active pharmaceutical ingredients (APIs) is
responsible for their poor performance and low drug levels in blood and at target sites …
responsible for their poor performance and low drug levels in blood and at target sites …
Analytical profiling of sofosbuvir as NS5B protein inhibitor for oral drug delivery: Method development and Validation
SW Rangari, SB Bari - Bulletin of Faculty of Pharmacy Cairo …, 2022 - bfopcu.eg.net
Hepatitis C virus (HCV) non-structural protein 5B (NS5B), which is being studied for its RNA-
dependent RNA polymerase (RDRP). It has been demonstrated that the RDRP is highly …
dependent RNA polymerase (RDRP). It has been demonstrated that the RDRP is highly …
A simple and sensitive HPLC-FL method for bioanalysis of velpatasvir, a novel hepatitis C virus NS5A inhibitor, in rat plasma: Investigation of factors determining its …
Velpatasvir is a novel inhibitor of hepatitis C virus nonstructural protein 5A that received US
Food and Drug Administration approval for the treatment of patients with chronic hepatitis C …
Food and Drug Administration approval for the treatment of patients with chronic hepatitis C …
Novel Hydrolytic Degradable Crosslinked Interpenetrating Polymeric Networks (IPNs): An Efficient Hybrid System to Manage the Controlled Release and Degradation …
Purpose: The goal of this study was to make pH-sensitive HPMC/Neocel C19-based
interpenetrating polymeric networks (IPNs) that could be used to treat different diseases. An …
interpenetrating polymeric networks (IPNs) that could be used to treat different diseases. An …
[PDF][PDF] RP-HPLC method to assay ethinylestradiol and drospirenone with 3D chromatograph model in fixed dose in rat plasma for pharmacokinetic study analysis.
For the simultaneous measurement of Ethinylestradiol (EE) and Drospirenone (DP) in fixed-
dose combination hormones tablets, a reverse-phase high-performance liquid …
dose combination hormones tablets, a reverse-phase high-performance liquid …
Analytical and Bioanalytical Methods for the Quantification of the Nucleotide Polymerase Inhibitor-Sofosbuvir: A Critical Review (2015-2021)
Sofosbuvir is a regularly used antiviral medication that was approved for clinical usage in
hepatitis C patients. Sofosbuvir belongs to the nucleotide analog drug class, and it operates …
hepatitis C patients. Sofosbuvir belongs to the nucleotide analog drug class, and it operates …
[PDF][PDF] Порівняльна характеристика сучасних методів аналізу противірусних препаратів з групи нуклеозидних аналогів-софосбувір та зидовудину
Д Аветисян - 2024 - dspace.nuph.edu.ua
У роботі проводиться огляд сучасних літературних джерел для визначення ключових
характеристик софосбувіру та зидовудину. Обрано та систематизовано методи …
характеристик софосбувіру та зидовудину. Обрано та систематизовано методи …
STABILITY INDICATING DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF SOFOSBUVIR AND VELPATASVIR RP-HPLC METHOD
V Yarasingi - World Journal of Pharmaceutical Sciences, 2024 - wjpsonline.com
Sofosbuvir and Velpatasvir were developed with Std Discovery 250 x 4.6 mm, 5m. Buffer-
containing MP OPA: MeCN in the 55: 45 ratio was poured across the column at 1 ml/min …
containing MP OPA: MeCN in the 55: 45 ratio was poured across the column at 1 ml/min …
Development and validation of single analytical HPLC method for determination of flavoxate HC1 in bulk, tablets and biological fluids.
AJ Rashid, S Bashir, NI Bukhari, N Abbas… - Pakistan Journal of …, 2021 - go.gale.com
A simple, sensitive and precise high performance liquid chromatographic (HPLC) method
was developed and validated for determination of flavoxate HCI in raw material, tablets and …
was developed and validated for determination of flavoxate HCI in raw material, tablets and …