Immune response and molecular mechanisms of cardiovascular adverse effects of spike proteins from SARS-CoV-2 and mRNA vaccines
The SARS-CoV-2 (severe acute respiratory syndrome coronavirus responsible for the
COVID-19 disease) uses the Spike proteins of its envelope for infecting target cells …
COVID-19 disease) uses the Spike proteins of its envelope for infecting target cells …
[HTML][HTML] Assessing the practice of biomedical ontology evaluation: Gaps and opportunities
With the proliferation of heterogeneous health care data in the last three decades,
biomedical ontologies and controlled biomedical terminologies play a more and more …
biomedical ontologies and controlled biomedical terminologies play a more and more …
OAE: the ontology of adverse events
Background A medical intervention is a medical procedure or application intended to relieve
or prevent illness or injury. Examples of medical interventions include vaccination and drug …
or prevent illness or injury. Examples of medical interventions include vaccination and drug …
[HTML][HTML] Causality assessment of adverse events following immunization: the problem of multifactorial pathology
P Bellavite - F1000Research, 2020 - ncbi.nlm.nih.gov
Abstract The analysis of Adverse Events Following Immunization (AEFI) is important in a
balanced epidemiological evaluation of vaccines and in the issues related to vaccine injury …
balanced epidemiological evaluation of vaccines and in the issues related to vaccine injury …
Adversomics: a new paradigm for vaccine safety and design
JA Whitaker, IG Ovsyannikova… - Expert review of …, 2015 - Taylor & Francis
Despite the enormous population benefits of routine vaccination, vaccine adverse events
(AEs) and reactions, whether real or perceived, have posed one of the greatest barriers to …
(AEs) and reactions, whether real or perceived, have posed one of the greatest barriers to …
COVID-19 vaccine design using reverse and structural vaccinology, ontology-based literature mining and machine learning
Rational vaccine design, especially vaccine antigen identification and optimization, is critical
to successful and efficient vaccine development against various infectious diseases …
to successful and efficient vaccine development against various infectious diseases …
Computational advances in drug safety: systematic and mapping review of knowledge engineering based approaches
Drug Safety (DS) is a domain with significant public health and social impact. Knowledge
Engineering (KE) is the Computer Science discipline elaborating on methods and tools for …
Engineering (KE) is the Computer Science discipline elaborating on methods and tools for …
Linking MedDRA®-Coded Clinical Phenotypes to Biological Mechanisms by the Ontology of Adverse Events: A Pilot Study on Tyrosine Kinase Inhibitors
S Sarntivijai, S Zhang, DG Jagannathan, S Zaman… - Drug safety, 2016 - Springer
Introduction A translational bioinformatics challenge exists in connecting population and
individual clinical phenotypes in various formats to biological mechanisms. The Medical …
individual clinical phenotypes in various formats to biological mechanisms. The Medical …
Ontology-based vaccine and drug adverse event representation and theory-guided systematic causal network analysis toward integrative pharmacovigilance research
Y He - Current pharmacology reports, 2016 - Springer
Compared with controlled terminologies (eg, MedDRA, CTCAE, and WHO-ART), the
community-based Ontology of Adverse Events (OAEs) has many advantages in AE …
community-based Ontology of Adverse Events (OAEs) has many advantages in AE …
Ontology-based precision vaccinology for deep mechanism understanding and precision vaccine development
J Xie, W Zi, Z Li, Y He - Current Pharmaceutical Design, 2021 - ingentaconnect.com
Vaccination is one of the most important innovations in human history. It has also become a
hot research area in a new application-the development of new vaccines against non …
hot research area in a new application-the development of new vaccines against non …