Background Polycystic ovarian syndrome (PCOS) is the most prevalent metabolic disorder
in reproductive-age women. It is indeed a multifactorial condition evidenced by ovarian …

Polycystic ovary syndrome (PCOS) is the most common endocrine diseases in women of
childbearing age that leads to menstrual disorders and infertility. The pathogenesis of PCOS …

MicroRNAs (miRNAs) are small, non-coding RNAs that are essential for the regulation of
post-transcriptional gene expression during tissue development and differentiation. They are …

Reproductive health is a worldwide challenge, but it is of particular significance to women
during their reproductive age. Several female reproductive problems, including polycystic …

Metformin, a synthetic derivative of guanidine, is commonly used as an oral antidiabetic
agent and is considered a multi-vector application agent in the treatment of other …

Polycystic ovary syndrome (PCOS) is a common disorder of the endocrine system. Its main
manifestations include oligo-ovulation, hyperandrogenism, and polycystic ovary morphology …

Abstract Treatment with metformin can lead to the recovery of pleiotropic biological activities
after spinal cord injury. However, its effect on spinal cord injury in aged mice remains …

As a complex endocrine and metabolic condition, polycystic ovarian syndrome (PCOS)
affects women's reproductive health. These common symptoms include hirsutism …

Purpose To characterize the mechanism by which metformin inhibits PD-L1 expression in
esophageal squamous cell carcinoma (ESCC) and to evaluate the effect of metformin on the …

Biological mediators secreted during peripheral chronic inflammation reach the bloodstream
and may damage the blood–brain barrier (BBB), triggering central nervous system (CNS) …