Cholestasis: Exploring the triangular relationship of gut microbiota-bile acid-cholestasis and the potential probiotic strategies

L Yu, Y Liu, S Wang, Q Zhang, J Zhao, H Zhang… - Gut …, 2023 - Taylor & Francis
Cholestasis is a condition characterized by the abnormal production or excretion of bile, and
it can be induced by a variety of causes, the factors of which are extremely complex …

Molecular pathogenesis of intrahepatic cholestasis of pregnancy

J Xiao, Z Li, Y Song, Y Sun, H Shi… - Canadian Journal of …, 2021 - Wiley Online Library
Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy‐specific liver disease. The
maternal symptoms are characterized by skin pruritus and elevated bile acids, causing …

Structure and function of hepatobiliary ATP binding cassette transporters

T Kroll, M Prescher, SHJ Smits, L Schmitt - Chemical reviews, 2020 - ACS Publications
The liver is beyond any doubt the most important metabolic organ of the human body. This
function requires an intensive crosstalk within liver cellular structures, but also with other …

[HTML][HTML] Liver disease in pregnancy: Medical aspects and their implications for mother and child

CS García-Romero, C Guzman, A Cervantes… - Annals of hepatology, 2019 - Elsevier
Liver disease during pregnancy is more common than expected and may require
specialized intervention. It is important to determine if changes in liver physiology may …

Rodent models of cholestatic liver disease: A practical guide for translational research

E Gijbels, A Pieters, K De Muynck, M Vinken… - Liver …, 2021 - Wiley Online Library
Cholestatic liver disease denotes any situation associated with impaired bile flow
concomitant with a noxious bile acid accumulation in the liver and/or systemic circulation …

UDCA, NorUDCA, and TUDCA in liver diseases: a review of their mechanisms of action and clinical applications

D Cabrera, JP Arab, M Arrese - Bile Acids and Their Receptors, 2019 - Springer
Bile acids (BAs) are key molecules in generating bile flow, which is an essential function of
the liver. In the last decades, there have been great advances in the understanding of BA …

Re‐evaluating diagnostic thresholds for intrahepatic cholestasis of pregnancy: case–control and cohort study

AL Mitchell, C Ovadia, A Syngelaki… - … Journal of Obstetrics …, 2021 - Wiley Online Library
Objective To determine the optimal total serum bile acid (TSBA) threshold and sampling time
for accurate intrahepatic cholestasis of pregnancy (ICP) diagnosis. Design Case–control …

Bile acids in intrahepatic cholestasis of pregnancy

M Majsterek, M Wierzchowska-Opoka, I Makosz… - Diagnostics, 2022 - mdpi.com
Intrahepatic cholestasis of pregnancy (ICP) is the most common, reversible, and closely
related to pregnancy condition characterized by elevated levels of bile acids (BAs) in blood …

The impact of intrahepatic cholestasis on pregnancy outcomes: a retrospective cohort study

Y Chen, H Zhang, W Ning, Y Chen, C Wen - BMC gastroenterology, 2023 - Springer
Background This study analyzed the pregnancy outcomes of patients with intrahepatic
cholestasis of pregnancy (ICP) in Hangzhou, China. Methods Cases of pregnant women …

[HTML][HTML] Guidelines for the management of cholestatic liver diseases (2021)

L Lu, Chinese Medical Association - Journal of Clinical and …, 2022 - ncbi.nlm.nih.gov
Abstract In 2015, the Chinese Society of Hepatology and the Chinese Society of
Gastroenterology issued a consensus statement on the diagnosis and management of …