Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics

R Tenchov, JM Sasso, X Wang, WS Liaw, CA Chen… - ACS …, 2022 - ACS Publications
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …

[HTML][HTML] Recent advances in exosome-mediated nucleic acid delivery for cancer therapy

Y Zhang, Q Liu, X Zhang, H Huang, S Tang… - Journal of …, 2022 - Springer
Cancer is a leading public health problem worldwide. Its treatment remains a daunting
challenge, although significant progress has been made in existing treatments in recent …

Recent insights into the nutritional immunomodulation of cancer‐related microRNAs

TÖ Şahin, B Yılmaz, N Yeşilyurt, D Cicia… - Phytotherapy …, 2023 - Wiley Online Library
Cancer is the most common cause of death worldwide, following cardiovascular diseases.
Cancer is a multifactorial disease and many reasons such as physical, chemical, biological …

Exosome: a significant nano-scale drug delivery carrier

H Peng, W Ji, R Zhao, J Yang, Z Lu, Y Li… - Journal of Materials …, 2020 - pubs.rsc.org
In recent years, due to the limitations of the nature of therapeutic agents, many synthetic
nano-delivery systems have emerged to enhance the efficacy of drugs. Extracellular vesicles …

[HTML][HTML] Exosomes engineering and their roles as therapy delivery tools, therapeutic targets, and biomarkers

N Kučuk, M Primožič, Ž Knez, M Leitgeb - International journal of …, 2021 - mdpi.com
Exosomes are becoming increasingly important therapeutic biomaterials for use in a variety
of therapeutic applications due to their unique characteristics, especially due to the …

Advances in bioactivity of microRNAs of plant-derived exosome-like nanoparticles and milk-derived extracellular vesicles

D Li, X Yao, J Yue, Y Fang, G Cao… - Journal of Agricultural …, 2022 - ACS Publications
MicroRNA (miRNA) is a class of small noncoding RNA involved in physiological and
pathological processes via the regulation of gene expression. Naked miRNAs are unstable …

Garlic-derived exosome-like nanovesicles alleviate dextran sulphate sodium-induced mouse colitis via the TLR4/MyD88/NF-κB pathway and gut microbiota …

Z Zhu, L Liao, M Gao, Q Liu - Food & function, 2023 - pubs.rsc.org
Plant-derived exosome-like nanovesicles play an important role in transferring their
biological cargos to recipient cells. The effect of garlic-derived exosome-like nanovesicles …

Identification of anti‐inflammatory vesicle‐like nanoparticles in honey

X Chen, B Liu, X Li, TT An, Y Zhou, G Li… - Journal of …, 2021 - Wiley Online Library
Honey has been used as a nutrient, an ointment, and a medicine worldwide for many
centuries. Modern research has demonstrated that honey has many medicinal properties …

[HTML][HTML] Apple derived exosomes improve collagen type I production and decrease MMPs during aging of the skin through downregulation of the NF-κB pathway as …

M Trentini, I Zanolla, F Zanotti, E Tiengo, D Licastro… - Cells, 2022 - mdpi.com
Skin ageing is strictly related to chronic inflammation of the derma and the decay of
structural proteins of the extracellular matrix. Indeed, it has become common practice to refer …

[HTML][HTML] Extracellular vesicle-shuttled miRNAs: a critical appraisal of their potential as nano-diagnostics and nano-therapeutics in type 2 diabetes mellitus and its …

F Prattichizzo, G Matacchione, A Giuliani… - Theranostics, 2021 - ncbi.nlm.nih.gov
Type 2 diabetes mellitus (T2DM) is a complex multifactorial disease causing the
development of a large range of cardiovascular (CV) complications. Lifestyle changes and …