Narcolepsy is a rare brain disorder that reflects a selective loss or dysfunction of orexin (also
known as hypocretin) neurons of the lateral hypothalamus. Narcolepsy type 1 (NT1) is …

Sleep disorders are frequent (18%–23%) and constitute a major risk factor for psychiatric,
cardiovascular, metabolic or hormonal co-morbidity and mortality. Low social status or …

Attention deficit/hyperactivity disorder (ADHD) is one of the most commonly diagnosed
disorders in childhood, enduring through adolescence and adulthood and presenting with …

Study objective To assess comorbidities in a community-based cohort of narcolepsy.
Methods A 2000–2014 community-based narcolepsy cohort was identified in Olmsted …

Study Objectives: Describe common symptoms, comorbidities, functional limitations, and
treatment responsiveness among patients with narcolepsy. Investigate the effect of pediatric …

Background Patients with unipolar disorder (UD) commonly experience cognitive
dysfunction during symptomatic and remitted phases. However, it is not necessarily the …

Narcolepsy is a rare chronic neurological disorder characterized by an irresistible excessive
daytime sleepiness and cataplexy. The disease is considered to be the result of the selective …

Narcolepsy type 1 is a life-long, severe, multifaceted disease often arising in childhood or
adolescence. Beyond the classical symptoms (excessive daytime sleepiness, cataplexy …

Orexins regulate a wide variety of biological functions, most notably the sleep-wake cycle,
reward and stress processing, alertness, vigilance, and cognitive functioning. Alterations of …

Objective The poor relationship between subjective and objective cognitive impairment in
bipolar disorder (BD) is well‐established. However, beyond simple correlation, this has not …