[HTML][HTML] Relapse of acute myeloid leukemia after allogeneic stem cell transplantation: immune escape mechanisms and current implications for therapy
T Sauerer, GF Velázquez, C Schmid - Molecular Cancer, 2023 - Springer
Acute myeloid leukemia (AML) is a heterogeneous disease characterized by the expansion
of immature myeloid cells in the bone marrow (BM) and peripheral blood (PB) resulting in …
of immature myeloid cells in the bone marrow (BM) and peripheral blood (PB) resulting in …
[HTML][HTML] Biomarkers as targets for CAR-T/NK cell therapy in AML
R Shao, Z Li, H Xin, S Jiang, Y Zhu, J Liu, R Huang… - Biomarker …, 2023 - Springer
The most common kind of acute leukemia in adults is acute myeloid leukemia (AML), which
is often treated with induction chemotherapy regimens followed by consolidation or …
is often treated with induction chemotherapy regimens followed by consolidation or …
Prospective PTCTC trial of myeloablative haplo-BMT with posttransplant cyclophosphamide for pediatric acute leukemias
Promising results have been reported for adult patients with high-risk hematologic
malignancies undergoing haploidentical bone marrow transplant (haploBMT) with …
malignancies undergoing haploidentical bone marrow transplant (haploBMT) with …
[HTML][HTML] A genome-wide association study on hematopoietic stem cell transplantation reveals novel genomic loci associated with transplant outcomes
A Rosenberger, RE Crossland, R Dressel… - Frontiers in …, 2024 - frontiersin.org
Introduction Data on genomic susceptibility for adverse outcomes after hematopoietic stem
cell transplantation (HSCT) for recipients are scarce. Methods We performed a genome wide …
cell transplantation (HSCT) for recipients are scarce. Methods We performed a genome wide …
[HTML][HTML] Allogeneic stem cell transplantation in the treatment of acute myeloid leukemia: An overview of obstacles and opportunities
YF Chen, J Li, LL Xu, MA Găman… - World Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
As an important treatment for acute myeloid leukemia, allogeneic hematopoietic stem cell
transplantation (allo-HSCT) plays an important role in reducing relapse and improving long …
transplantation (allo-HSCT) plays an important role in reducing relapse and improving long …
[HTML][HTML] Checkpoint inhibitors in acute myeloid leukemia
D Damiani, M Tiribelli - Biomedicines, 2023 - mdpi.com
The prognosis of acute myeloid leukemia (AML) remains unsatisfactory. Among the reasons
for the poor response to therapy and high incidence of relapse, there is tumor cell immune …
for the poor response to therapy and high incidence of relapse, there is tumor cell immune …
[HTML][HTML] Novel strategies to prevent and overcome relapse after allogeneic hematopoietic cell transplantation in acute lymphoblastic leukemia
MH Hodroj, I Abou Dalle, N Moukalled… - Frontiers in …, 2023 - frontiersin.org
The outcome of B-cell acute lymphoblastic leukemia (B-ALL) has improved over time with
the incorporation of multi-agent chemotherapy in the treatment landscape as well as the …
the incorporation of multi-agent chemotherapy in the treatment landscape as well as the …
[HTML][HTML] Allogeneic Hematopoietic Cell Transplantation in Advanced Systemic Mastocytosis: A retrospective analysis of the DRST and GREM registries
J Lübke, D Christen, J Schwaab, A Kaiser, N Naumann… - Leukemia, 2024 - nature.com
We identified 71 patients with AdvSM (aggressive SM [ASM], SM with an associated
hematologic neoplasm [SM-AHN, eg, acute myeloid leukemia, SM-AML], mast cell leukemia …
hematologic neoplasm [SM-AHN, eg, acute myeloid leukemia, SM-AML], mast cell leukemia …
Improvements in Posttransplant Outcomes Over Two Decades in Older Patients with Acute Myeloid Leukemia in the EBMT ALWP Study
Purpose: Acute myeloid leukemia (AML) is a disease of older patients. Progress in
allogeneic hematopoietic cell transplantation (allo-HCT) allowed the delivery of allo-HCT to …
allogeneic hematopoietic cell transplantation (allo-HCT) allowed the delivery of allo-HCT to …
The role and novel use of natural killer cells in graft-versus-leukemia reactions after allogeneic transplantation
AD Hadjis, SR McCurdy - Frontiers in Immunology, 2024 - frontiersin.org
Allogeneic hematopoietic cell transplantation (HCT) has transformed over the past several
decades through enhanced supportive care, reduced intensity conditioning (RIC), improved …
decades through enhanced supportive care, reduced intensity conditioning (RIC), improved …