Biological functions of mesenchymal stem cells and clinical implications
Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
Regenerative capacity of adipose derived stem cells (ADSCs), comparison with mesenchymal stem cells (MSCs)
L Mazini, L Rochette, M Amine, G Malka - International journal of …, 2019 - mdpi.com
Adipose tissue is now on the top one of stem cell sources regarding its accessibility,
abundance, and less painful collection procedure when compared to other sources. The …
abundance, and less painful collection procedure when compared to other sources. The …
Concise review: mesenchymal stem cells in neurodegenerative diseases
Stem cell-based therapies for neurodegenerative diseases aim at halting clinical
deterioration by regeneration and by providing local support for damaged tissue …
deterioration by regeneration and by providing local support for damaged tissue …
Mammalian MSC from selected species: Features and applications
C Uder, S Brückner, S Winkler… - Cytometry Part …, 2018 - Wiley Online Library
Mesenchymal stromal/stem cells (MSC) are promising candidates for cellular therapy of
different diseases in humans and in animals. Following the guidelines of the International …
different diseases in humans and in animals. Following the guidelines of the International …
Stereotactic brain injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer's disease dementia: a phase 1 clinical trial
HJ Kim, SW Seo, JW Chang, JI Lee… - … Research & Clinical …, 2015 - Wiley Online Library
Introduction We conducted a phase 1 clinical trial in nine patients with mild‐to‐moderate
Alzheimer's disease to evaluate the safety and dose‐limiting toxicity of stereotactic brain …
Alzheimer's disease to evaluate the safety and dose‐limiting toxicity of stereotactic brain …
Phase I trial of repeated intrathecal autologous bone marrow-derived mesenchymal stromal cells in amyotrophic lateral sclerosis
Stem cell therapy is an emerging alternative therapeutic or disease-modifying strategy for
amyotrophic lateral sclerosis (ALS). The aim of this open-label phase I clinical trial was to …
amyotrophic lateral sclerosis (ALS). The aim of this open-label phase I clinical trial was to …
Therapeutic utility of mesenchymal stromal cell (MSC)-based approaches in chronic neurodegeneration: a glimpse into underlying mechanisms, current status, and …
M Rahbaran, AO Zekiy, M Bahramali… - Cellular & Molecular …, 2022 - Springer
Recently, mesenchymal stromal cell (MSC)-based therapy has become an appreciated
therapeutic approach in the context of neurodegenerative disease therapy. Accordingly, a …
therapeutic approach in the context of neurodegenerative disease therapy. Accordingly, a …
TGF-β and mesenchymal stromal cells in regenerative medicine, autoimmunity and cancer
V de Araújo Farias, AB Carrillo-Gálvez, F Martin… - Cytokine & Growth …, 2018 - Elsevier
Multipotent mesenchymal stromal cells (MSCs) represent a promising cell-based therapy in
regenerative medicine and for the treatment of inflammatory/autoimmune diseases …
regenerative medicine and for the treatment of inflammatory/autoimmune diseases …
Repeated intrathecal mesenchymal stem cells for amyotrophic lateral sclerosis
Objective To assess the safety and efficacy of 2 repeated intrathecal injections of autologous
bone marrow–derived mesenchymal stem cells (BM‐MSCs) in amyotrophic lateral sclerosis …
bone marrow–derived mesenchymal stem cells (BM‐MSCs) in amyotrophic lateral sclerosis …
Hydrogel culture surface stiffness modulates mesenchymal stromal cell secretome and alters senescence
ME Ogle, G Doron, MJ Levy… - Tissue Engineering Part …, 2020 - liebertpub.com
Current cell culture surfaces used for the expansion and production of mesenchymal stromal
cells (MSCs) are not optimized for the production of highly secretory and nonsenescent …
cells (MSCs) are not optimized for the production of highly secretory and nonsenescent …