[HTML][HTML] Biocompatible polymer nanoparticles for drug delivery applications in cancer and neurodegenerative disorder therapies

E Calzoni, A Cesaretti, A Polchi, A Di Michele… - Journal of functional …, 2019 - mdpi.com
Polymer nanoparticles (NPs) represent one of the most innovative non-invasive approaches
for drug delivery applications. NPs main objective is to convey the therapeutic molecule be …

Polymeric micelles for anticancer drug delivery

N Majumder, NG Das, SK Das - Therapeutic delivery, 2020 - Taylor & Francis
Polymeric micelles have gained interest as novel drug delivery systems for the treatment
and diagnosis of cancer, as they offer several advantages over conventional drug therapies …

EGFR targeting for cancer therapy: Pharmacology and immunoconjugates with drugs and nanoparticles

E da Silva Santos, KAB Nogueira… - International journal of …, 2021 - Elsevier
The epidermal growth factor receptor (EGFR) belongs to the tyrosine kinase receptors family
and is present in the epithelial cell membrane. Its endogenous activation occurs through the …

Nanoparticles in nanomedicine: a comprehensive updated review on current status, challenges and emerging opportunities

HM Abdel-Mageed, NZ AbuelEzz… - Journal of …, 2021 - Taylor & Francis
The fast progress in nanomedicine and nanoparticles (NP) materials presents
unconventional solutions which are expected to revolutionise health care with great …

Controlled release and targeted drug delivery with poly (lactic-co-glycolic acid) nanoparticles: reviewing two decades of research

A Zeb, M Gul, TTL Nguyen, HJ Maeng - Journal of Pharmaceutical …, 2022 - Springer
Background Controlled release and targeted delivery of the drug payload are the two most
fascinating applications of nanoparticle-based systems explored in the recent past. The …

[HTML][HTML] Docetaxel-loaded solid lipid nanoparticles prevent tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells

MCO da Rocha, PB da Silva, MA Radicchi… - Journal of …, 2020 - Springer
Background Metastasis causes the most breast cancer-related deaths in women. Here, we
investigated the antitumor effect of solid lipid nanoparticles (SLN-DTX) when used in the …

An overview of micronanoswarms for biomedical applications

H Chen, H Zhang, T Xu, J Yu - ACS nano, 2021 - ACS Publications
Micronanoswarms have attracted extensive attention worldwide due to their great promise in
biomedical applications. The collective behaviors among thousands, or even millions, of tiny …

[HTML][HTML] Recent advances in the surface functionalization of PLGA-based nanomedicines

MM El-Hammadi, JL Arias - Nanomaterials, 2022 - mdpi.com
Therapeutics are habitually characterized by short plasma half-lives and little affinity for
targeted cells. To overcome these challenges, nanoparticulate systems have entered into …

Triple negative breast cancer and non-small cell lung cancer: Clinical challenges and nano-formulation approaches

S Ghosh, A Javia, S Shetty, D Bardoliwala… - Journal of Controlled …, 2021 - Elsevier
Triple negative breast cancer (TNBC) and non-small cell lung cancer (NSCLC) are amongst
the most aggressive forms of solid tumors. TNBC is highlighted by absence of genetic …

[HTML][HTML] A quantitative view on multivalent nanomedicine targeting

L Woythe, NB Tito, L Albertazzi - Advanced drug delivery reviews, 2021 - Elsevier
Although the concept of selective delivery has been postulated over 100 years ago, no
targeted nanomedicine has been clinically approved so far. Nanoparticles modified with …