[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance

H Marshall, NJ Stewart, HF Chan, M Rao… - Progress in Nuclear …, 2021 - Elsevier
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …

Enabling Clinical Technologies for Hyperpolarized 129Xenon Magnetic Resonance Imaging and Spectroscopy

AS Khan, RL Harvey, JR Birchall… - Angewandte Chemie …, 2021 - Wiley Online Library
Hyperpolarization is a technique that can increase nuclear spin polarization with the
corresponding gains in nuclear magnetic resonance (NMR) signals by 4–8 orders of …

Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe …

PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …

Long-lived enhanced magnetization—A practical metabolic MRI contrast material

I Katz, A Schmidt, I Ben-Shir, M Javitt, K Kouřil… - Science …, 2024 - science.org
Noninvasive tracking of biochemical processes in the body is paramount in diagnostic
medicine. Among the leading techniques is spectroscopic magnetic resonance imaging …

Time-series hyperpolarized xenon-129 MRI of lobar lung ventilation of COPD in comparison to V/Q-SPECT/CT and CT

O Doganay, T Matin, M Chen, M Kim, A McIntyre… - European …, 2019 - Springer
Purpose To derive lobar ventilation in patients with chronic obstructive pulmonary disease
(COPD) using a rapid time-series hyperpolarized xenon-129 (HPX) magnetic resonance …

Lung Volume Dependence and Repeatability of Hyperpolarized 129Xe MRI Gas Uptake Metrics in Healthy Volunteers and Participants with …

WJ Garrison, K Qing, M He, L Zhao… - Radiology …, 2023 - pubs.rsna.org
Purpose To assess the effect of lung volume on measured values and repeatability of xenon
129 (129Xe) gas uptake metrics in healthy volunteers and participants with chronic …

Characterisation of gas exchange in COPD with dissolved-phase hyperpolarised xenon-129 MRI

L Myc, K Qing, M He, N Tustison, Z Lin… - Thorax, 2021 - thorax.bmj.com
To investigate whether hyperpolarised xenon-129 MRI (HXeMRI) enables regional and
physiological resolution of diffusing capacity limitations in chronic obstructive pulmonary …

Mapping cardiopulmonary dynamics within the microvasculature of the lungs using dissolved 129Xe MRI

PJ Niedbalski, EA Bier, Z Wang… - Journal of Applied …, 2020 - journals.physiology.org
Magnetic resonance (MR) imaging and spectroscopy using dissolved hyperpolarized (HP)
129Xe have expanded the ability to probe lung function regionally and noninvasively. In …

Hyperpolarized gas imaging in lung diseases: functional and artificial intelligence perspective

Z Zhang, H Li, S Xiao, Q Zhou, S Liu, X Zhou, L Fan - Academic Radiology, 2024 - Elsevier
Pathophysiologic changes in lung diseases are often accompanied by changes in
ventilation and gas exchange. Comprehensive evaluation of lung function cannot be …

Gas exchange and ventilation imaging of healthy and COPD subjects using hyperpolarized xenon-129 MRI and a 3D alveolar gas-exchange model

O Doganay, M Kim, FV Gleeson - European Radiology, 2023 - Springer
Objectives To investigate the utility of hyperpolarized xenon-129 (HPX) gas-exchange
magnetic resonance imaging (MRI) and modeling in a chronic obstructive pulmonary …