[HTML][HTML] Pathogenesis and clinical management of obesity-related knee osteoarthritis: Impact of mechanical loading

L Chen, JJY Zheng, G Li, J Yuan, JR Ebert, H Li… - Journal of orthopaedic …, 2020 - Elsevier
Obesity-related osteoarthritis (OA) is a complex, multifactorial condition that can cause
significant impact on patients' quality of life. Whilst chronic inflammation, adipocytokines and …

Knee kinematics, cartilage morphology, and osteoarthritis after ACL injury.

AM Chaudhari, PL Briant, SL Bevill, S Koo… - Medicine and science …, 2008 - europepmc.org
This review examines a mechanism for the initiation of osteoarthritis after anterior cruciate
ligament (ACL) injury by considering the relationship between reported ambulatory changes …

Topographic orientation of scaffolds for tissue regeneration: recent advances in biomaterial design and applications

J Chi, M Wang, J Chen, L Hu, Z Chen, LJ Backman… - Biomimetics, 2022 - mdpi.com
Tissue engineering to develop alternatives for the maintenance, restoration, or
enhancement of injured tissues and organs is gaining more and more attention. In tissue …

The acetabular labrum: a review of its function

S Bsat, H Frei, PE Beaulé - The bone & joint journal, 2016 - boneandjoint.org.uk
The acetabular labrum is a soft-tissue structure which lines the acetabular rim of the hip joint.
Its role in hip joint biomechanics and joint health has been of particular interest over the past …

Mechanical properties of normal and osteoarthritic human articular cartilage

DL Robinson, ME Kersh, NC Walsh, DC Ackland… - Journal of the …, 2016 - Elsevier
Isotropic hyperelastic models have been used to determine the material properties of normal
human cartilage, but there remains an incomplete understanding of how these properties …

Characterization of articular cartilage by combining microscopic analysis with a fibril-reinforced finite-element model

P Julkunen, P Kiviranta, W Wilson, JS Jurvelin… - Journal of …, 2007 - Elsevier
Load-bearing characteristics of articular cartilage are impaired during tissue degeneration.
Quantitative microscopy enables in vitro investigation of cartilage structure but determination …

[图书][B] Articular cartilage

KA Athanasiou, EM Darling, JC Hu, GD DuRaine… - 2017 - taylorfrancis.com
This book covers the latest research and advancements related to articular cartilage in
biology, development, pathology, clinical applications and tissue engineering. The authors …

A novel mechanobiological model can predict how physiologically relevant dynamic loading causes proteoglycan loss in mechanically injured articular cartilage

GA Orozco, P Tanska, C Florea, AJ Grodzinsky… - Scientific reports, 2018 - nature.com
Cartilage provides low-friction properties and plays an essential role in diarthrodial joints. A
hydrated ground substance composed mainly of proteoglycans (PGs) and a fibrillar collagen …

Influence of weak hip abductor muscles on joint contact forces during normal walking: probabilistic modeling analysis

G Valente, F Taddei, I Jonkers - Journal of biomechanics, 2013 - Elsevier
The weakness of hip abductor muscles is related to lower-limb joint osteoarthritis, and joint
overloading may increase the risk for disease progression. The relationship between muscle …

Quantitative evaluation of the mechanical risks caused by focal cartilage defects in the knee

MS Venäläinen, ME Mononen, J Salo, LP Räsänen… - Scientific reports, 2016 - nature.com
Focal cartilage lesions can proceed to severe osteoarthritis or remain unaltered even for
years. A method to identify high risk defects would be of utmost importance to guide clinical …