The neural basis of psychedelic action

AC Kwan, DE Olson, KH Preller, BL Roth - Nature Neuroscience, 2022 - nature.com
Psychedelics are serotonin 2A receptor agonists that can lead to profound changes in
perception, cognition and mood. In this review, we focus on the basic neurobiology …

[HTML][HTML] Psychedelics and neuroplasticity: a systematic review unraveling the biological underpinnings of psychedelics

CMH De Vos, NL Mason, KPC Kuypers - Frontiers in psychiatry, 2021 - frontiersin.org
Clinical studies suggest the therapeutic potential of psychedelics, including ayahuasca,
DMT, psilocybin, and LSD, in stress-related disorders. These substances induce cognitive …

International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function

NM Barnes, GP Ahern, C Becamel, J Bockaert… - Pharmacological …, 2021 - ASPET
5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …

Psychedelics

DE Nichols - Pharmacological reviews, 2016 - ASPET
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

Biochemical mechanisms underlying psychedelic-induced neuroplasticity

DE Olson - Biochemistry, 2022 - ACS Publications
In addition to producing profound subjective effects following acute administration,
psychedelic compounds can induce beneficial behavioral changes relevant to the treatment …

[HTML][HTML] The role of serotonin 5-HT2A receptors in memory and cognition

G Zhang, RW Stackman Jr - Frontiers in pharmacology, 2015 - frontiersin.org
Serotonin 5-HT2A receptors (5-HT2ARs) are widely distributed in the central nervous
system, especially in brain region essential for learning and cognition. In addition to …

Recent advances in the neuropsychopharmacology of serotonergic hallucinogens

AL Halberstadt - Behavioural brain research, 2015 - Elsevier
Abstract Serotonergic hallucinogens, such as (+)-lysergic acid diethylamide, psilocybin, and
mescaline, are somewhat enigmatic substances. Although these drugs are derived from …

Platelets and cancer: a casual or causal relationship: revisited

DG Menter, SC Tucker, S Kopetz, AK Sood… - Cancer and Metastasis …, 2014 - Springer
Human platelets arise as subcellular fragments of megakaryocytes in bone marrow. The
physiologic demand, presence of disease such as cancer, or drug effects can regulate the …

Hallucinogens

DE Nichols - Pharmacology & therapeutics, 2004 - Elsevier
Hallucinogens (psychedelics) are psychoactive substances that powerfully alter perception,
mood, and a host of cognitive processes. They are considered physiologically safe and do …

Hallucinogens and Serotonin 5-HT2A Receptor-Mediated Signaling Pathways

JF López-Giménez, J González-Maeso - Behavioral neurobiology of …, 2018 - Springer
The neuropsychological effects of naturally occurring psychoactive chemicals have been
recognized for millennia. Hallucinogens, which include naturally occurring chemicals such …