Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective

S Kumariya, V Ubba, RK Jha, JR Gayen - Autophagy, 2021 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a unification of endocrine and metabolic disorders and
has become immensely prevalent among women of fertile age. The prime organ affected in …

[HTML][HTML] Metabolic dysfunction in polycystic ovary syndrome: Pathogenic role of androgen excess and potential therapeutic strategies

MA Sanchez-Garrido, M Tena-Sempere - Molecular metabolism, 2020 - Elsevier
Background Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among
reproductive age women. Although its cardinal manifestations include hyperandrogenism …

Developing biomedical engineering technologies for reproductive medicine

Y Zhu, B Kong, R Liu, Y Zhao - Smart Medicine, 2022 - Wiley Online Library
Infertility is a rising global health issue with a far‐reaching impact on the socioeconomic
livelihoods. As there are highly complex causes of male and female infertility, it is highly …

[HTML][HTML] Polycystic ovary syndrome and cardiometabolic risk: Opportunities for cardiovascular disease prevention

O Osibogun, O Ogunmoroti, ED Michos - Trends in cardiovascular …, 2020 - Elsevier
Although polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders
affecting women, its etiology is not entirely understood. Clinical symptoms of PCOS include …

Genetic basis of polycystic ovary syndrome (PCOS): current perspectives

MJ Khan, A Ullah, S Basit - The application of clinical genetics, 2019 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a common infertility disorder affecting a significant
proportion of the global population. It is the main cause of anovulatory infertility in women …

The pathogenesis of polycystic ovary syndrome (PCOS): the hypothesis of PCOS as functional ovarian hyperandrogenism revisited

RL Rosenfield, DA Ehrmann - Endocrine reviews, 2016 - academic.oup.com
Polycystic ovary syndrome (PCOS) was hypothesized to result from functional ovarian
hyperandrogenism (FOH) due to dysregulation of androgen secretion in 1989–1995 …

Progesterone actions and resistance in gynecological disorders

JA MacLean, K Hayashi - Cells, 2022 - mdpi.com
Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …

Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood

B Tata, NEH Mimouni, AL Barbotin, SA Malone… - Nature medicine, 2018 - nature.com
Polycystic ovary syndrome (PCOS) is the main cause of female infertility worldwide and
corresponds with a high degree of comorbidities and economic burden. How PCOS is …

[HTML][HTML] Follicle stimulating hormone (LH: FSH) ratio in polycystic ovary syndrome (PCOS)-obese vs. non-obese women

Z Saadia - Medical Archives, 2020 - ncbi.nlm.nih.gov
Aim: This study aimed to compare normal and high Body mass index (BMI) women with
PCOS and to investigate the correlation between BMI and LH/FSH ratio. Methods: It was a …

Polycystic ovarian syndrome (PCOS): Long-term metabolic consequences

P Anagnostis, BC Tarlatzis, RP Kauffman - Metabolism, 2018 - Elsevier
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women during
their reproductive ages, associated with a plethora of cardiometabolic consequences, with …